Anti-hypervariable region antibody induced by a defined peptide: an approach for studying the structural correlates of idiotypes
about
General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acidsCloning and sequence determination of a human rheumatoid factor light-chain geneCharacterization of human rheumatoid factors with seven antiidiotypes induced by synthetic hypervariable region peptides.Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.Idiotypic markers of polyclonal B cell activation. Public idiotypes shared by monoclonal antibodies derived from patients with systemic lupus erythematosus or leprosy.Construction of an extended three-dimensional idiotope map by electron microscopic analysis of idiotope-anti-idiotope complexesComplete protein sequences of the variable regions of the cloned heavy and light chains of a human anti-cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic family.Evolutionary origin of autoreactive determinants (autogens)Characterization of an epibody. An antiidiotype that reacts with both the idiotype of rheumatoid factors (RF) and the antigen recognized by RF.Syngeneic antiidiotypic immune responses to a B cell lymphoma. Comparison between heavy chain hypervariable region peptides and intact Ig as immunogens.Synthetic peptides corresponding to third hypervariable region of human monoclonal IgM rheumatoid factor heavy chains define an immunodominant idiotypeComplete amino acid sequences of variable regions of two human IgM rheumatoid factors, BOR and KAS of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segmentsIdiotypic cascades associated with the CD4-HIV gp120 interaction: principles for idiotype-based vaccines.NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritisGenetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies.From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all.Topographic analysis with monoclonal anti-idiotopes: probing the functional anatomy of immunoglobulin variable domains.Perspectives on antigenicity and idiotypy.The use of defined peptides in characterizing idiotypes.
P2860
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P2860
Anti-hypervariable region antibody induced by a defined peptide: an approach for studying the structural correlates of idiotypes
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Anti-hypervariable region anti ...... ctural correlates of idiotypes
@ast
Anti-hypervariable region anti ...... ctural correlates of idiotypes
@en
type
label
Anti-hypervariable region anti ...... ctural correlates of idiotypes
@ast
Anti-hypervariable region anti ...... ctural correlates of idiotypes
@en
prefLabel
Anti-hypervariable region anti ...... ctural correlates of idiotypes
@ast
Anti-hypervariable region anti ...... ctural correlates of idiotypes
@en
P2093
P2860
P356
P1476
Anti-hypervariable region anti ...... ctural correlates of idiotypes
@en
P2093
D A Carson
G H Rhodes
J H Vaughan
R A Houghten
R A Lerner
T A Gilbertson
P2860
P304
P356
10.1073/PNAS.81.6.1784
P407
P577
1984-03-01T00:00:00Z