Complete amino acid sequences of variable regions of two human IgM rheumatoid factors, BOR and KAS of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segments
about
Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapyRheumatoid factors from the peripheral blood of two patients with rheumatoid arthritis are genetically heterogeneous and somatically mutatedHepatitis C virus and non-Hodgkin's lymphomas: Meta-analysis of epidemiology data and therapy optionsA rheumatoid factor paradox: inhibition of rituximab effector function.Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal.Can antiglycolipid antibodies present in HIV-infected individuals induce immune demyelination?The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidencRelationship of the CD5 B cell to human tonsillar lymphocytes that express autoantibody-associated cross-reactive idiotypesDevelopmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia.Nucleotidic sequence analysis of the variable domains of four human monoclonal IgM with an antibody activity to myelin-associated glycoprotein.Human heavy-chain variable region gene family nonrandomly rearranged in familial chronic lymphocytic leukemia.Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.Rheumatoid factor V genes from patients with rheumatoid arthritis are diverse and show evidence of an antigen-driven response.Complete protein sequences of the variable regions of the cloned heavy and light chains of a human anti-cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic family.Kappa/lambda immunoglobulin distribution in Graves' thyroid-stimulating antibodies. Simultaneous analysis of C lambda gene polymorphisms.The antigen-binding domain of a human IgG-anti-F(ab')2 autoantibody.Human rheumatoid B-1a (CD5+ B) cells make somatically hypermutated high affinity IgM rheumatoid factorsEvidence for somatic selection of natural autoantibodies.Complete sequence of the genes encoding the VH and VL regions of low- and high-affinity monoclonal IgM and IgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient.Isolation and characterization of a light chain variable region gene for human rheumatoid factorsDistinct patterns of heavy chain variable region subgroup use by human monoclonal autoantibodies of different specificity.Autoantibodies encoded by the most Jh-proximal human immunoglobulin heavy chain variable region gene.Expression of a public idiotype by human monoclonal IgM directed to myelin-associated glycoprotein and characterization of the variability subgroup of their heavy and light chains.Molecular characterization of a cross-reactive idiotope on human immunoglobulins utilizing the VH4-21 gene segment.Human rheumatoid factor cross-idiotypes. IV. Studies on WA XId-positive IgM without rheumatoid factor activity provide evidence that the WA XId is not unique to rheumatoid factors and is distinct from the 17.109 and G6 XIds.Expression of the immunoglobulin VH gene 51p1 is proportional to its germline gene copy number.Heavy chain variable region gene utilization in human antibodies.From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all.Immunoglobulin gene sequence analysis to further assess B-cell origin of multiple myeloma.Rheumatoid factor autoantibodies in health and disease.Characterization of two highly homologous autoantibody-related VH1 genes in humans.Immunogenic and antigenic epitopes of immunoglobulins. XXIII. Idiotypy and molecular specificity of human rheumatoid factors: analysis of cross-reactive idiotype of rheumatoid factor paraproteins from the Wa idiotype group in relation to their IgG sA human rheumatoid factor C304 shares VH and VL gene usage with antibodies specific for ubiquitous human viral pathogens.Stereotypic rheumatoid factors that are frequently expressed in mucosa-associated lymphoid tissue-type lymphomas are rare in the labial salivary glands of patients with Sjögren's syndrome.Monozygotic Rheumatoid Arthritis Twin Pairs Express Similar Levels of Conserved Immunoglobulin V Gene in Polyclonal Rheumatoid Factors Irrespective of Disease Status
P2860
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P2860
Complete amino acid sequences of variable regions of two human IgM rheumatoid factors, BOR and KAS of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segments
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
Complete amino acid sequences ...... d joining region gene segments
@ast
Complete amino acid sequences ...... d joining region gene segments
@en
type
label
Complete amino acid sequences ...... d joining region gene segments
@ast
Complete amino acid sequences ...... d joining region gene segments
@en
prefLabel
Complete amino acid sequences ...... d joining region gene segments
@ast
Complete amino acid sequences ...... d joining region gene segments
@en
P2093
P2860
P356
P1476
Complete amino acid sequences ...... d joining region gene segments
@en
P2093
P2860
P304
P356
10.1084/JEM.166.2.550
P407
P577
1987-08-01T00:00:00Z