Genetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies.
about
Conservation of sequence in recombination signal sequence spacersRheumatoid factors isolated from patients with autoimmune disorders are derived from germline genes distinct from those encoding the Wa, Po, and Bla cross-reactive idiotypes.Physical map of the 3' region of the human immunoglobulin heavy chain locus: clustering of autoantibody-related variable segments in one haplotypeIdiotypes and anti-idiotypes: what are they trying to tell us?Possible deletion of a developmentally regulated heavy-chain variable region gene in autoimmune diseases.A novel upstream element compensates for an ineffectual octamer motif in an immunoglobulin V kappa promoter.Evidence of antigen receptor-influenced oligoclonal B lymphocyte expansion in the synovium of a patient with longstanding rheumatoid arthritis.Immunochemistry of DNA.Variable region sequences of a protective human monoclonal antibody specific for the Haemophilus influenzae type b capsular polysaccharideIdiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.CD5 negative IGM rheumatoid factor B cells in B-chronic lymphocytic leukemia and benign mixed cryoglobulinemia.Complete protein sequences of the variable regions of the cloned heavy and light chains of a human anti-cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic family.Human antibody responses to bacterial antigens: studies of a model conventional antigen and a proposed model B cell superantigen.Isolation and characterization of a light chain variable region gene for human rheumatoid factorsA shared idiotype among human anti-Ro/SSA autoantibodies.Molecular characterization of a cross-reactive idiotope on human immunoglobulins utilizing the VH4-21 gene segment.Human anti-self antibodies with high specificity from phage display libraries.Genetic analysis of the variable region genes encoding a monospecific human natural anti-DNA antibody.From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all.Somatic mutations in B lymphocytes: new perspectives in tolerance research?The use of defined peptides in characterizing idiotypes.The structural repertoire of the human V kappa domainGermline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.The human immunoglobulin kappa locus: pseudogenes, unique and repetitive sequences.A minor group of rheumatoid factors isolated from a patient with rheumatoid arthritis is derived from somatically mutated Vk1 genes further evidence that rheumatoid factors during autoimmune diseases undergo an antigen driven maturation.
P2860
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P2860
Genetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Genetic basis for the cross-re ...... n IgM anti-IgG autoantibodies.
@en
Genetic basis for the cross-re ...... n IgM anti-IgG autoantibodies.
@nl
type
label
Genetic basis for the cross-re ...... n IgM anti-IgG autoantibodies.
@en
Genetic basis for the cross-re ...... n IgM anti-IgG autoantibodies.
@nl
prefLabel
Genetic basis for the cross-re ...... n IgM anti-IgG autoantibodies.
@en
Genetic basis for the cross-re ...... n IgM anti-IgG autoantibodies.
@nl
P2093
P2860
P356
P1476
Genetic basis for the cross-re ...... n IgM anti-IgG autoantibodies.
@en
P2093
D A Carson
K Albrandt
R Schrantz
P2860
P304
P356
10.1073/PNAS.83.21.8318
P407
P577
1986-11-01T00:00:00Z