Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

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Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure.Discovery of new GPCR ligands to illuminate new biology.Trends in GPCR drug discovery: new agents, targets and indications.

P2860

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P2860

Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

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http://www.wikidata.org/entity/Q36263056

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

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Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

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Item

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Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

@ast

Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

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Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

@ast

Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

@en

P1476

Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

@en

P2093

Alem W Kahsai

http://www.w3.org/2001/XMLSchema#string

Alissa L Wall

http://www.w3.org/2001/XMLSchema#string

Biswaranjan Pani

http://www.w3.org/2001/XMLSchema#string

Bryant J Gavino

http://www.w3.org/2001/XMLSchema#string

Daniel L Bassoni

http://www.w3.org/2001/XMLSchema#string

Dean P Staus

http://www.w3.org/2001/XMLSchema#string

Eva K Olsen

http://www.w3.org/2001/XMLSchema#string

Gitte Husemoen

http://www.w3.org/2001/XMLSchema#string

Gwenn M Hansen

http://www.w3.org/2001/XMLSchema#string

Jane E Lamerdin

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P2860

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

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Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007

Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR)

In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors

Determining allosteric modulator mechanism of action: integration of radioligand binding and functional assay data.

P304

1708-1713

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P31

scholarly article

P356

10.1073/PNAS.1620645114

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

114

http://www.w3.org/2001/XMLSchema#string

P50

Stefano Costanzi

Laura M Wingler

Justine Sinnaeve

P577

2017-01-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28130548

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P932

5321036

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Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

about

P2860

P2860

Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932