about
Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stabilityRequirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cellsA genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stabilityA DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signalingDEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survivalTyrosine dephosphorylation of H2AX modulates apoptosis and survival decisionsATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repairA genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repairBAP1 is phosphorylated at serine 592 in S-phase following DNA damageGermline mutations in BAP1 predispose to melanocytic tumorsThe ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expressionCellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor RadiosensitizationMultiple Functions of the Eya Phosphotyrosine PhosphataseDNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosisStructural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2A quaternary mechanism enables the complex biological functions of octameric human UDP-glucose pyrophosphorylase, a key enzyme in cell metabolismFunctional genomics identifies negative regulatory nodes controlling phagocyte oxidative burstCell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteinsATR: an essential regulator of genome integrityUV-C irradiation delays mitotic progression by recruiting Mps1 to kinetochoresSynaptic activity bidirectionally regulates a novel sequence-specific S-Q phosphoproteome in neuronsMislocalization of the MRN complex prevents ATR signaling during adenovirus infection.Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.Kinetics of the UV-induced DNA damage response in relation to cell cycle phase. Correlation with DNA replication.A proteome-wide analysis of kinase-substrate network in the DNA damage response.Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaksProliferating cell nuclear antigen-dependent rapid recruitment of Cdt1 and CRL4Cdt2 at DNA-damaged sites after UV irradiation in HeLa cells.Mass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cellsThe menin tumor suppressor protein is phosphorylated in response to DNA damageRequirement of MTA1 in ATR-mediated DNA damage checkpoint function.Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometrymTORC1 directly phosphorylates and regulates human MAF1.Phosphoproteomics by mass spectrometry: insights, implications, applications and limitations.BAP1 loss defines a new class of renal cell carcinoma.Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaksAn S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control.Phosphoproteomics in cancerSMAR1 coordinates HDAC6-induced deacetylation of Ku70 and dictates cell fate upon irradiation.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Profiling of UV-induced ATM/ATR signaling pathways.
@ast
Profiling of UV-induced ATM/ATR signaling pathways.
@en
type
label
Profiling of UV-induced ATM/ATR signaling pathways.
@ast
Profiling of UV-induced ATM/ATR signaling pathways.
@en
prefLabel
Profiling of UV-induced ATM/ATR signaling pathways.
@ast
Profiling of UV-induced ATM/ATR signaling pathways.
@en
P2093
P2860
P50
P356
P1476
Profiling of UV-induced ATM/ATR signaling pathways
@en
P2093
Jian Min Ren
Joan Macneill
Julie Nardone
Kam Sprott
Matthew P Stokes
Michael J Comb
Roberto D Polakiewicz
Vicky Yang
P2860
P304
19855-19860
P356
10.1073/PNAS.0707579104
P407
P577
2007-12-06T00:00:00Z