Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures - Wikidata - awgldk - TriplyDB

Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures

Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures

http://www.wikidata.org/entity/Q36293998

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Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer Potential mechanisms underlying the Runx2 induced osteogenesis of bone marrow mesenchymal stem cells Transcriptional regulatory cascades in Runx2-dependent bone development Cbfa1/RUNX2 directs specific expression of the sclerosteosis gene (SOST)Runx2- and histone deacetylase 3-mediated repression is relieved in differentiating human osteoblast cells to allow high bone sialoprotein expression Regulation of adult bone turnover by sex steroids Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects Parathyroid hormone-responsive Smad3-related factor, Tmem119, promotes osteoblast differentiation and interacts with the bone morphogenetic protein-Runx2 pathway The high mobility group transcription factor Sox8 is a negative regulator of osteoblast differentiation Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter CCN3 protein participates in bone regeneration as an inhibitory factor SP7 inhibits osteoblast differentiation at a late stage in mice Identification of a new pebp2alphaA2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro.Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs.Thrombospondin-2 regulates matrix mineralization in MC3T3-E1 pre-osteoblasts.Guangxi cobra venom-derived NGF promotes the osteogenic and therapeutic effects of porous BCP ceramic.Osterix enhances proliferation and osteogenic potential of bone marrow stromal cells.Prostaglandin E2 inhibits matrix mineralization by human bone marrow stromal cell-derived osteoblasts via Epac-dependent cAMP signaling Osterix overexpression in mesenchymal stem cells stimulates healing of critical-sized defects in murine calvarial bone Maintenance of Bone Homeostasis by DLL1-Mediated Notch Signaling Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells.Overexpression of Bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis.Deficiency of chemokine receptor CCR1 causes osteopenia due to impaired functions of osteoclasts and osteoblasts.Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage.Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading.Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice.Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.Runx2 activity in committed osteoblasts is not essential for embryonic skeletogenesis.Regulatory mechanisms of osteoblast and osteoclast differentiation.Loss of Runx2 in committed osteoblasts impairs postnatal skeletogenesis.Runx2, a multifunctional transcription factor in skeletal development.Roles of SATB2 in osteogenic differentiation and bone regeneration Parathyroid hormone controls receptor activator of NF-kappaB ligand gene expression via a distant transcriptional enhancer.Control of osteoblast function and regulation of bone mass.Loss of osteoblast Runx3 produces severe congenital osteopenia

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Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures

http://www.wikidata.org/entity/Q36293998

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2001 nî lūn-bûn

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2001年學術文章

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Overexpression of Cbfa1 in ost ...... openia with multiple fractures

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Overexpression of Cbfa1 in ost ...... openia with multiple fractures

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Overexpression of Cbfa1 in ost ...... openia with multiple fractures

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Overexpression of Cbfa1 in ost ...... openia with multiple fractures

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Overexpression of Cbfa1 in ost ...... openia with multiple fractures

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Overexpression of Cbfa1 in ost ...... openia with multiple fractures

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Overexpression of Cbfa1 in ost ...... openia with multiple fractures

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Furuichi T

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Himeno M

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Kanatani N

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Komori T

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Liu W

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Liu Y

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Narai S

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Toyosawa S

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Yamaguchi A

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Yoshida C

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P2860

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

Maturational disturbance of chondrocytes in Cbfa1-deficient mice

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

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