Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase
about
Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cellsDifferential regulation of cell motility and invasion by FAKRETRACTED: TGFβ1 signaling via αVβ6 integrinActivation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation.NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding modelPAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activationMechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cellsPTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substratesThe alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesisC-terminal heparin-binding domain of fibronectin regulates integrin-mediated cell spreading but not the activation of mitogen-activated protein kinaseFocal adhesion kinase protein levels in gut epithelial motilityVinexin beta regulates the anchorage dependence of ERK2 activation stimulated by epidermal growth factor.The v-Src SH3 domain facilitates a cell adhesion-independent association with focal adhesion kinase.Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS.Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis.Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cellsPerlecan up-regulation of FRNK suppresses smooth muscle cell proliferation via inhibition of FAK signalingFocal adhesion kinase and endothelial cell apoptosis.Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells.Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell linesCD13 regulates anchorage and differentiation of the skeletal muscle satellite stem cell population in ischemic injury.Growth defects induced by perturbation of beta1-integrin function in the mammary gland epithelium result from a lack of MAPK activation via the Shc and Akt pathways.Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer.Inhibition of cell growth and spreading by stomach cancer-associated protein-tyrosine phosphatase-1 (SAP-1) through dephosphorylation of p130cas.Order and disorder: the role of extracellular matrix in epithelial cancer.The contradictions of the insulin-like growth factor 1 receptor.Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations.Biological significance of focal adhesion kinase in ovarian cancer: role in migration and invasionDifferential expression of FAK and Pyk2 in metastatic and non-metastatic EL4 lymphoma cell linesTranscriptional regulation of the cyclin D1 gene at a glance.Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB.Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor cross-talk in unanchored cellsErbB receptors and epithelial-cadherin-catenin complex in human carcinomas.Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness.Synergistic control of cell adhesion by integrins and syndecans.Focal adhesion kinase modulates cell adhesion strengthening via integrin activation.Integrins are required for the differentiation of visceral endodermEffect of disrupting seven-in-absentia homolog 2 function on lung cancer cell growthFocal adhesion kinase signaling in cardiac hypertrophy and failure.Ionizing radiation and glioblastoma exosomes: implications in tumor biology and cell migration
P2860
Q24336373-3C49147B-EB57-4C83-8CF3-BF0FE23F5F7CQ24673170-B20B9572-A8BA-435E-A312-96AD2631E67DQ24795499-38FE7689-1FBE-45AB-9F0F-899E35ECE15DQ24816886-8ED60A1A-91E5-4042-97BF-66454E698F4DQ27642755-07E5609D-75E1-48D2-9D52-026D2CC4330BQ28188974-AFCB9AEA-94C4-4C47-9E49-3C5020194409Q28213888-C1836D99-8B00-48B3-BFBE-04E886E7D0DBQ28343311-567B4932-47C5-46CE-A724-46A8B8CE0365Q28344804-134A0554-7F27-4DB1-9520-10C0B96A0323Q28363354-F21FDD95-1D10-46FB-8E04-C855E13957DAQ28578373-02079969-FF4F-4F6C-9731-69EEE907C43AQ30167641-1645B983-5788-48EF-9D63-4C2C8E781A18Q30168345-B7060F8A-B8C3-4786-833C-7ACFB6C31A05Q30424126-62C1F7AB-8844-42A1-8EFB-C531751215D2Q30441862-9CEF6817-DD17-4F18-9671-584E6421102AQ30442000-9E9F1500-7833-4291-87F9-50B2408D1ED1Q30452968-D5C44C40-0410-456D-86B1-7EE38B12729FQ30459602-8B1EBD77-1C51-4B74-AFB5-9A78C2959FD1Q30496969-38C403AA-9031-4FA6-9245-B2BA01A4402FQ33384571-48B5B912-6AB5-4FCA-AB77-FFAD1C4F6B29Q33680416-C9974EF1-9266-4C77-8CD4-C6BFB03DBE87Q33757347-DAF9CD23-8A99-4156-8666-4C9DB69CA752Q33892756-E6E2960B-57FE-4847-BF14-EFC28C774B89Q33940349-EFF30691-FDC0-4F93-BD97-B14F4D8CF551Q34103413-67B1EAC1-3286-4753-8B9A-732139FEC7F2Q34103628-88D62B6A-57D2-4B65-9DFD-4C3E4FDC4E52Q34991305-AEA7DBE4-B560-402E-8C65-09DC1F5B6EA7Q35103303-18E4F073-20A3-4E0F-8911-6B8E942346CCQ35353329-24B8A606-0A97-4D69-8DBA-3B3513CA4DAEQ35985157-34866523-C8C2-4B5A-9FFC-2835A9692580Q36392027-29D4DAB2-A714-42D9-AAAC-16B41FF3BCE5Q36586280-BFFB0286-83BB-433D-B5FB-4F6BD083D9D4Q36677496-C5E7FA99-17CA-4653-B942-C2E9A6E0F896Q36943119-AF963594-B3F9-43BC-97B7-E63FBF1C91C4Q36986535-1E410BC1-8559-4B8D-91ED-1DA0ED2F89A9Q37175419-6C1B0E89-5BD3-4478-B1AD-1B5C4ADEC8B5Q37271595-E6A32ADD-C27A-4A93-A183-08AC6192F10EQ37289054-6A421F7B-C66B-47EA-B36E-4A8670BB5339Q37393800-29497AA6-C5A4-40CE-86CC-29B9B56B4196Q37474338-FBF14503-9CCF-48EC-B68C-2CDFEB982047
P2860
Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Focal adhesion kinase mediates ...... actor activation of MAP kinase
@ast
Focal adhesion kinase mediates ...... actor activation of MAP kinase
@en
type
label
Focal adhesion kinase mediates ...... actor activation of MAP kinase
@ast
Focal adhesion kinase mediates ...... actor activation of MAP kinase
@en
prefLabel
Focal adhesion kinase mediates ...... actor activation of MAP kinase
@ast
Focal adhesion kinase mediates ...... actor activation of MAP kinase
@en
P2093
P2860
P356
P1476
Focal adhesion kinase mediates ...... actor activation of MAP kinase
@en
P2093
M A Schwartz
M W Renshaw
P2860
P304
P356
10.1083/JCB.147.3.611
P407
P577
1999-11-01T00:00:00Z