Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. - Wikidata - awgldk - TriplyDB

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

http://www.wikidata.org/entity/Q36301943

about

Tracheal development and the von Hippel-Lindau tumor suppressor homolog in Drosophila Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/Hif-1alpha/VEGF signaling Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast Vanadate-induced expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways Hypoxia and oxidative stress in breast cancer. Hypoxia and tumourigenesis Breast cancer-induced angiogenesis: multiple mechanisms and the role of the microenvironment Lactate Dehydrogenase in Hepatocellular Carcinoma: Something Old, Something New Hypoxic control of metastasis Pharmacologic resistance in colorectal cancer: a review The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications Hypoxia and Integrin-Mediated Epithelial Restitution during Mucosal Inflammation Hepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1 and Stimulates the Synthesis of Vascular Endothelial Growth Factor VHL mutations and their correlation with tumour cell proliferation, microvessel density, and patient prognosis in clear cell renal cell carcinoma.The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells Chick embryo partial ischemia model: a new approach to study ischemia ex vivo A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein.Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics The impact of O2 availability on human cancer Regulation of hypoxia adaptation: an overlooked virulence attribute of pathogenic fungi?A conserved helical capping hydrogen bond in PAS domains controls signaling kinetics in the superfamily prototype photoactive yellow protein.Overhauser enhanced magnetic resonance imaging for tumor oximetry: coregistration of tumor anatomy and tissue oxygen concentration.Molecular mechanism of hypoxia-inducible factor 1alpha -p300 interaction. A leucine-rich interface regulated by a single cysteine.Tumoral environment triggers transcript anomalies in established tumors: induction of altered gene expression and of aberrant, truncated and B2 repeat-containing gene transcripts Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1).A novel role for 3, 4-dichloropropionanilide (DCPA) in the inhibition of prostate cancer cell migration, proliferation, and hypoxia-inducible factor 1alpha expression.Xenopus Dab2 is required for embryonic angiogenesis

P2860

Q22254253-CB3B6EAE-5E88-4D9D-BE08-3AEC899C467E Q24610199-CB83637D-7552-44D1-A2FF-D188F03AAA02 Q24652148-E82C97D6-EA76-46E0-BEAD-F687B432894D Q24672058-57C2B700-4BB7-4391-AE22-7827927219F8 Q24685857-2879BD15-6B3A-4601-BBD6-3D2D68230B77 Q24720804-597B5A65-FD9F-44B3-92D4-04F36BECD482 Q24797535-AD4DAB7B-292D-4BC2-A941-7EA293D876AC Q24800550-595E55FF-8191-4104-8225-B50911AA33A5 Q24801701-DEEC2EA1-2AC9-445F-98FB-0C23D733D3C7 Q24801724-8D0D38C7-C21A-43D6-B004-32ECFC9194E7 Q24803543-AB2000CD-A5C4-43CE-88C3-EDB0FE0A26DA Q26744542-36A0F88C-5224-47F6-B644-BFBA81FA7D5A Q26749159-0876FC86-DABA-4C7F-81A2-9CA0D284DC62 Q26769850-AEB84DC7-56B0-47F7-8856-0196C348AD99 Q26829663-917BA2C2-3405-46DE-9BA7-FFEF7C29E75D Q26995631-592EF496-86CF-416D-B78C-FC1ED40C8B22 Q27481487-7C806087-44A1-4EC0-803E-90F748498C0A Q27824781-4AED71C9-967A-4217-8AE8-AC9B7B0D338E Q28143066-6C7612B3-23B7-4DAC-90C1-0B73121C1108 Q28211384-3BDF3021-2EE4-4BD0-B706-4402BC7D5E58 Q28283184-126B5004-F722-4D75-946F-B51CC8F08BBD Q28352584-B7505237-2756-4092-A7E6-90B30D66D52B Q28363133-E5F0A45E-2040-4682-A0D2-E57D95DA5C84 Q28365260-FDC1DD03-C6CC-4C3B-832E-09AB3114569C Q28394160-54EEAF58-CA54-48C8-9C8F-3BC9DCC3F3B0 Q28473867-70C31514-BCED-4A21-8143-CF1C785A4AA3 Q28473962-9524C68E-5DD3-45E1-B030-60D76E19C76F Q28512092-1F416ED4-7A46-49DD-8482-1CB2323EDD67 Q28590550-EAA87D32-E2FB-4B7F-B66F-3BC3FFD8FF72 Q28678484-8864531C-AC0D-4A0E-AE11-3A4962C826DF Q29615944-501DAC03-7AAE-4371-8A93-1528D07ABC4E Q29619884-DB3FAC0A-E6C6-4726-BD88-79D75B9EC7D6 Q30377415-D7094DA4-14B3-4409-8710-0E83074523C4 Q30394963-3F29EDB5-FD67-493E-A017-4D628650AACA Q30675008-9B05A3D3-0948-4F24-ADDF-09F5E42164A5 Q31527917-8D99B009-CC88-48A7-9F63-F31BC6FBE83C Q31802557-4C9C6E07-BDBD-4BBC-B011-0F640EC29E54 Q33235403-42819F3E-EE13-472E-95E5-FCC778CEAA5E Q33252625-227EB3F7-E923-4D88-AE0D-5A1E38822857 Q33266946-088CEAF3-984A-4A51-A2EC-25E4457E0097

P2860

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

http://www.wikidata.org/entity/Q36301943

description

1997 nî lūn-bûn

@nan

1997年の論文

@ja

1997年学术文章

@wuu

1997年学术文章

@zh-cn

1997年学术文章

@zh-hans

1997年学术文章

@zh-my

1997年学术文章

@zh-sg

1997年學術文章

@yue

1997年學術文章

@zh

1997年學術文章

@zh-hant

name

Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.

@ast

Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.

@en

type

label

Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.

@ast

Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.

@en

prefLabel

Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.

@ast

Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.

@en

P1433

Q36301943-19CBCBBE-2104-4214-83C7-1ECCC0B896C3

P1476

Q36301943-87B801C9-9BD0-4075-ADD2-7A84694A5802

P2093

Q36301943-1B09D599-9BE6-4F7A-B113-FC8B7327A6D0

Q36301943-7A04C91B-4B67-45CD-A52B-26D2416AE122

Q36301943-7A6B9DD7-1CBD-4590-8C98-91F75A67B499

Q36301943-D1E674A9-8F97-4729-ADF8-24A07DE8711B

Q36301943-D2FEC4F6-E9CF-43F2-8339-E03E5BCD2C54

P2860

Q36301943-19579748-83DB-4235-9B8B-BE00F84A32A1

Q36301943-1EE3D680-2CD5-4BD3-B7F4-453C20E9290F

Q36301943-2BF28C4F-9D29-4B73-9F1A-FB6EA594FB1F

Q36301943-35D1C5FE-DE6F-4409-B0C1-DE1A7F8D5E56

Q36301943-36D03604-8D84-4230-A952-6B78379FD2EE

Q36301943-37041610-0AE5-4539-8F60-9D6E403C7947

Q36301943-44B699A3-FD65-4AF6-8E66-AE25418DB788

Q36301943-46670F73-796D-43B2-A1F4-0900B9BCD83B

Q36301943-51B07FF5-0456-45E6-8142-7815EA78BA2E

Q36301943-6A377254-AB06-4002-9FA6-62F70DE15DFF

P304

Q36301943-7767E33B-71EC-4C60-BB37-68E862DCE87B

P31

Q36301943-9A94A3EA-282E-45F7-8A9E-A62BDCE94EF3

P356

Q36301943-94AEA1E2-184A-4801-9509-B52FC790C2BD

P407

Q36301943-3706E4D0-3489-4302-A5C9-FFF30AAC77EF

P433

Q36301943-F5B6AC5B-9405-4321-B41E-76207F9528A3

P478

Q36301943-0F82326E-5E62-43BC-BDCE-1CD7FADE70A2

P50

Q36301943-70E35C8F-1AA9-4207-AF0C-F4219678917A

Q36301943-8510675F-63BF-48F8-9BD2-8679AAE1E728

Q36301943-86C37DD9-FE24-4C5B-92BA-BA2FC04AC0DB

Q36301943-D48B5AED-75F1-47A3-A336-4E94F850DD02

P577

Q36301943-D533D993-7D4A-43FF-B627-88100533F8F5

P5875

Q36301943-F9BAD336-ECA6-4FAE-B1BA-226CF6A51B7E

P698

Q36301943-7BC66ED8-9153-4739-A2DD-462F2C0B61B5

P921

Q36301943-6220D77C-99DA-4893-9906-1A7682F99012

P932

Q36301943-6A7AA941-CD38-4281-9E7D-BA452105030D

P356

PNAS.94.15.8104

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth

@en

P2093

C W Pugh

http://www.w3.org/2001/XMLSchema#string

G U Dachs

http://www.w3.org/2001/XMLSchema#string

L G Nicholls

http://www.w3.org/2001/XMLSchema#string

O Hankinson

http://www.w3.org/2001/XMLSchema#string

P H Maxwell

http://www.w3.org/2001/XMLSchema#string

P2860

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

Cloning of a factor required for activity of the Ah (dioxin) receptor

Mechanism of action of a repressor of dioxin-dependent induction of Cyp1a1 gene transcription

Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha

P304

8104-8109

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.94.15.8104

http://www.w3.org/2001/XMLSchema#string

P407

P433

15

http://www.w3.org/2001/XMLSchema#string

P478

94

http://www.w3.org/2001/XMLSchema#string

P50

Peter J. Ratcliffe

Jonathan M. Gleadle

Adrian L Harris

Ian J Stratford

P577

1997-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

13996922

http://www.w3.org/2001/XMLSchema#string

P698

9223322

http://www.w3.org/2001/XMLSchema#string

P921

P932

21564

http://www.w3.org/2001/XMLSchema#string