about
GADD45 proteins: central players in tumorigenesisAstrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegenerationAstrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-MycStem cells as cellular vehicles for gene therapy against glioblastomaTargeting the Bcl-2 family for cancer therapyDeveloping an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinicMDA-7/IL-24 induces Bcl-2 denitrosylation and ubiquitin-degradation involved in cancer cell apoptosisTherapy of prostate cancer using a novel cancer terminator virus and a small molecule BH-3 mimeticRecombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells.Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancerCisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cellsEradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach.Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24BI-69A11 enhances susceptibility of colon cancer cells to mda-7/IL-24-induced growth inhibition by targeting AktMDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant gliomaPERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.Characterization of the canine mda-7 gene, transcripts and expression patterns.Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas.Tumour suppressor function of MDA-7/IL-24 in human breast cancerThe development of MDA-7/IL-24 as a cancer therapeuticA first-generation multi-functional cytokine for simultaneous optical tracking and tumor therapyMelanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress.Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.Reversing translational suppression and induction of toxicity in pancreatic cancer cells using a chemoprevention gene therapy approachGene therapy as an adjuvant treatment for malignant gliomas: from bench to bedside.Enhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV).Targeting breast cancer-initiating/stem cells with melanoma differentiation-associated gene-7/interleukin-24.Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.Autophagy: cancer's friend or foe?Gene Therapies for Cancer: Strategies, Challenges and Successes.mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokineAd-REIC Gene Therapy: Promising Results in a Patient with Metastatic CRPC Following ChemotherapyEnhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cellsmda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer.mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokineStrategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomasMolecular Mechanisms Governing IL-24 Gene Expression.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Is mda-7/IL-24 a "magic bullet" for cancer?
@ast
Is mda-7/IL-24 a "magic bullet" for cancer?
@en
type
label
Is mda-7/IL-24 a "magic bullet" for cancer?
@ast
Is mda-7/IL-24 a "magic bullet" for cancer?
@en
prefLabel
Is mda-7/IL-24 a "magic bullet" for cancer?
@ast
Is mda-7/IL-24 a "magic bullet" for cancer?
@en
P1433
P1476
Is mda-7/IL-24 a "magic bullet" for cancer?
@en
P2093
Paul B Fisher
P304
10128-10138
P356
10.1158/0008-5472.CAN-05-3127
P407
P577
2005-11-01T00:00:00Z