Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets.
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Evidence that the primary binding site of von Willebrand factor that mediates platelet adhesion on subendothelium is not collagenStructure of platelet glycoprotein IIIa. A common subunit for two different membrane receptorsLateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3Detection of high-risk atherosclerotic plaques with ultrasound molecular imaging of glycoprotein IIb/IIIa receptor on activated platelets.Epitope mapping by cDNA expression of a monoclonal antibody which inhibits the binding of von Willebrand factor to platelet glycoprotein IIb/IIIa.On the association of the platelet-specific alloantigen, Pena, with glycoprotein IIIa. Evidence for heterogeneity of glycoprotein IIIa.Von Willebrand's disease with spontaneous platelet aggregation induced by an abnormal plasma von Willebrand factor.Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo.von Willebrand factor binds to platelets and induces aggregation in platelet-type but not type IIB von Willebrand diseasePlatelets have more than one binding site for von Willebrand factor.Functional self-association of von Willebrand factor during platelet adhesion under flow.A deletion in the gene for glycoprotein IIb associated with Glanzmann's thrombastheniaGlanzmann thrombasthenia resulting from a single amino acid substitution between the second and third calcium-binding domains of GPIIb. Role of the GPIIb amino terminus in integrin subunit associationArginine-glycine-aspartic acid- and fibrinogen gamma-chain carboxyterminal peptides inhibit platelet adherence to arterial subendothelium at high wall shear rates. An effect dissociable from interference with adhesive protein binding.Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function.A myeloma paraprotein with specificity for platelet glycoprotein IIIa in a patient with a fatal bleeding disorder.Asialo von Willebrand factor interactions with platelets. Interdependence of glycoproteins Ib and IIb/IIIa for binding and aggregation.Functionally thrombasthenic state in normal platelets following the administration of ticlopidine.A monoclonal antibody to human platelet glycoprotein IIIa detects a related protein in cultured human endothelial cells.A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complexFibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate.Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody.von Willebrand factor interaction with the glycoprotein IIb/IIa complex. Its role in platelet function as demonstrated in patients with congenital afibrinogenemia.Interaction of von Willebrand factor with human platelets in the plasma milieuInteraction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation.Platelet adhesion under flow.Effects of monoclonal antibodies against the platelet glycoprotein IIb/IIIa complex on thrombosis and hemostasis in the baboon.Fibronectin degradation products containing the cytoadhesive tetrapeptide stimulate human neutrophil degranulation.Platelet glycoproteins Ia, Ic, and IIa are physicochemically indistinguishable from the very late activation antigens adhesion-related proteins of lymphocytes and other cell types.Kistrin, an integrin antagonist, blocks endocytosis of fibrinogen into guinea pig megakaryocyte and platelet alpha-granules.Localization of internal pools of membrane glycoproteins involved in platelet adhesive responses.Platelet-collagen adhesion: evidence for participation of antigenically distinct entities.Glycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets.Von Willebrand factor promotes endothelial cell adhesion via an Arg-Gly-Asp-dependent mechanism.Differential structural requirements for fibrinogen binding to platelets and to endothelial cells.Evidence for the selective association of a subpopulation of GPIIb-IIIa with the actin cytoskeletons of thrombin-activated platelets.Prothrombin activation by platelet-associated prothrombinase proceeds through the prethrombin-2 pathway via a concerted mechanism.Platelet integrins and immunoreceptors.A monomeric von Willebrand factor fragment, Leu-504--Lys-728, inhibits von Willebrand factor interaction with glycoprotein Ib-IX [corrected]Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells.
P2860
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P2860
Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets.
description
1982 nî lūn-bûn
@nan
1982年の論文
@ja
1982年学术文章
@wuu
1982年学术文章
@zh-cn
1982年学术文章
@zh-hans
1982年学术文章
@zh-my
1982年学术文章
@zh-sg
1982年學術文章
@yue
1982年學術文章
@zh
1982年學術文章
@zh-hant
name
Glanzmann thrombasthenia: defi ...... thrombin-stimulated platelets.
@ast
Glanzmann thrombasthenia: defi ...... thrombin-stimulated platelets.
@en
type
label
Glanzmann thrombasthenia: defi ...... thrombin-stimulated platelets.
@ast
Glanzmann thrombasthenia: defi ...... thrombin-stimulated platelets.
@en
prefLabel
Glanzmann thrombasthenia: defi ...... thrombin-stimulated platelets.
@ast
Glanzmann thrombasthenia: defi ...... thrombin-stimulated platelets.
@en
P2093
P2860
P356
P1476
Glanzmann thrombasthenia: defi ...... thrombin-stimulated platelets.
@en
P2093
P2860
P304
P356
10.1073/PNAS.79.19.6038
P407
P577
1982-10-01T00:00:00Z