Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements. - Wikidata - awgldk - TriplyDB

Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements.

Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements.

http://www.wikidata.org/entity/Q36321175

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Biochemical characterization of three BLT receptors in zebrafish Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton Shp2 knockdown and Noonan/LEOPARD mutant Shp2-induced gastrulation defects Diaphanous-related formin 2 and profilin I are required for gastrulation cell movements PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation.LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.Prenylation-deficient G protein gamma subunits disrupt GPCR signaling in the zebrafish Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization.S1pr2/Gα13 signaling controls myocardial migration by regulating endoderm convergence.Gpr125 modulates Dishevelled distribution and planar cell polarity signaling.Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway.Integration of contractile forces during tissue invagination SDF1-induced antagonism of axonal repulsion requires multiple G-protein coupled signaling components that work in parallel Ror2 receptor mediates Wnt11 ligand signaling and affects convergence and extension movements in zebrafish.Temporal control over the initiation of cell motility by a regulator of G-protein signaling Def6 is required for convergent extension movements during zebrafish gastrulation downstream of Wnt5b signaling.Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation.The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.Heterotrimeric G-protein alpha-12 (Gα12) subunit promotes oral cancer metastasis.Syntaxin 16 regulates lumen formation during epithelial morphogenesis.Whole-exome sequencing identifies homozygous GPR161 mutation in a family with pituitary stalk interruption syndrome.Protein phosphatase 1 β paralogs encode the zebrafish myosin phosphatase catalytic subunit Gβγ signaling controls the polarization of zebrafish primordial germ cells by regulating Rac activity A dynamic intracellular distribution of Vangl2 accompanies cell polarization during zebrafish gastrulation The orphan G protein-coupled receptor 161 is required for left-right patterning Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation A role of glypican4 and wnt5b in chondrocyte stacking underlying craniofacial cartilage morphogenesis Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling.Calcium signaling in vertebrate embryonic patterning and morphogenesis From individual Wnt pathways towards a Wnt signalling network.The emerging role of Wnt/PCP signaling in organ formation.Role of G12 proteins in oncogenesis and metastasis Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer.Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity Collective epithelial and mesenchymal cell migration during gastrulation.A perspective on more effective GPCR-targeted drug discovery efforts.Gβ1 controls collective cell migration by regulating the protrusive activity of leader cells in the posterior lateral line primordium.Gα13 is closely related to hematopoiesis in zebrafish.Gβ1 is required for neutrophil migration in zebrafish.

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Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements.

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Fang Lin

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Songhai Chen

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P2860

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

Stages of embryonic development of the zebrafish

Bmp activity gradient regulates convergent extension during zebrafish gastrulation

Convergent extension: the molecular control of polarized cell movement during embryonic development

Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1

Signaling by the G12 class of G proteins

Cell movements during epiboly and gastrulation in zebrafish

The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish

Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP

The many faces of G protein signaling

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