A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation. - Wikidata - awgldk - TriplyDB

A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation.

A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation.

http://www.wikidata.org/entity/Q36323606

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Fibroblast growth factor signaling in skeletal development and disease PP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues.Pocket proteins and cell cycle control Sixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias Meclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasia Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal.Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence NF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cells PP2A-mediated dephosphorylation of p107 plays a critical role in chondrocyte cell cycle arrest by FGF Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage New insight on FGFR3-related chondrodysplasias molecular physiopathology revealed by human chondrocyte gene expression profiling A Network Map of FGF-1/FGFR Signaling System.Mutant activated FGFR3 impairs endochondral bone growth by preventing SOX9 downregulation in differentiating chondrocytes Thrombospondin-2 influences the proportion of cartilage and bone during fracture healing.Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models.Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype FGF signaling in the developing endochondral skeleton.Reversine Increases the Plasticity of Long-Term Cryopreserved Fibroblasts to Multipotent Progenitor Cells through Activation of Oct4.FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth.Exercise-driven metabolic pathways in healthy cartilage.Cell type-specific control of protein synthesis and proliferation by FGF-dependent signaling to the translation repressor 4E-BP.Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55α holoenzyme.Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytes A Track Record on SHOX: From Basic Research to Complex Models and Therapy FGFR3 targeting strategies for achondroplasia.Cross-talk between FGF and other cytokine signalling pathways during endochondral bone development.Current understanding on the molecular basis of chondrogenesis.The chondrocytic journey in endochondral bone growth and skeletal dysplasia.Phosphoproteomics of Fibroblast Growth Factor 1 (FGF1) Signaling in Chondrocytes: Identifying the Signature of Inhibitory Response.A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.Achondroplasia: Development, pathogenesis, and therapy.The B55α regulatory subunit of protein phosphatase 2A mediates fibroblast growth factor-induced p107 dephosphorylation and growth arrest in chondrocytes.Overexpression of cyclin E/CDK2 complexes overcomes FGF-induced cell cycle arrest in the presence of hypophosphorylated Rb proteins FGF inhibits the activity of the cyclin B1/CDK1 kinase to induce a transient G₂arrest in RCS chondrocytes.Fibroblast growth factor signaling uses multiple mechanisms to inhibit Wnt-induced transcription in osteoblasts.Indian hedgehog signaling pathway differences between swarm rat chondrosarcoma and native rat chondrocytes.

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P2860

A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation.

http://www.wikidata.org/entity/Q36323606

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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A network of transcriptional a ...... th arrest and differentiation.

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A network of transcriptional a ...... th arrest and differentiation.

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A network of transcriptional a ...... th arrest and differentiation.

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A network of transcriptional a ...... th arrest and differentiation.

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A network of transcriptional a ...... th arrest and differentiation.

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A network of transcriptional a ...... th arrest and differentiation.

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Claudio Basilico

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Emmanuel Laplantine

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Lisa Dailey

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Riccardo Priore

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P2860

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

CDK inhibitors: positive and negative regulators of G1-phase progression

The Myc/Max/Mad network and the transcriptional control of cell behavior

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?

Basic helix-loop-helix protein DEC1 promotes chondrocyte differentiation at the early and terminal stages

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

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