The Fanconi Anemia/BRCA pathway: new faces in the crowd.
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityFAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathwayFanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repairFANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3RTEL1 maintains genomic stability by suppressing homologous recombinationChk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repairUAF1 is a subunit of multiple deubiquitinating enzyme complexesDNA polymerase POLN participates in cross-link repair and homologous recombinationRad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrestHomologous recombination in DNA repair and DNA damage toleranceThe DNA-damage response in human biology and diseaseHow the fanconi anemia pathway guards the genomeRegulation and cellular roles of ubiquitin-specific deubiquitinating enzymesTelomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenitaChk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathwayThe Fanconi anemia pathway and DNA interstrand cross-link repairApplication of toxicogenomic profiling to evaluate effects of benzene and formaldehyde: from yeast to humanSapacitabine for cancerFormation of a N 2 -dG: N 2 -dG Carbinolamine DNA Cross-link by the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -dG AdductStructural insights into the functions of the FANCM-FAAP24 complex in DNA repairRegulation of monoubiquitinated PCNA by DUB autocleavageRegulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitinationA comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assayFANCI protein binds to DNA and interacts with FANCD2 to recognize branched structuresForkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage responseHES1 is a novel interactor of the Fanconi anemia core complexHCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stabilityFormaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessmentDeletion of Fanca or Fancd2 dysregulates Treg in miceConcomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalusOuabain, a cardiac glycoside, inhibits the Fanconi anemia/BRCA pathway activated by DNA interstrand cross-linking agentsBRCA2 is required for neurogenesis and suppression of medulloblastomaExpanded roles of the Fanconi anemia pathway in preserving genomic stabilityThe Fanconi anemia pathway and ubiquitinHuman DHX9 helicase unwinds triple-helical DNA structuresMolecular profiles of hereditary epithelial ovarian cancers and their implications for the biology of this disease.FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein.Mph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination.Fanconi anemia proteins stabilize replication forks.Remodeling of DNA replication structures by the branch point translocase FANCM
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P2860
The Fanconi Anemia/BRCA pathway: new faces in the crowd.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The Fanconi Anemia/BRCA pathway: new faces in the crowd.
@ast
The Fanconi Anemia/BRCA pathway: new faces in the crowd.
@en
type
label
The Fanconi Anemia/BRCA pathway: new faces in the crowd.
@ast
The Fanconi Anemia/BRCA pathway: new faces in the crowd.
@en
prefLabel
The Fanconi Anemia/BRCA pathway: new faces in the crowd.
@ast
The Fanconi Anemia/BRCA pathway: new faces in the crowd.
@en
P356
P1433
P1476
The Fanconi Anemia/BRCA pathway: new faces in the crowd.
@en
P2093
Alan D D'Andrea
Richard D Kennedy
P304
P356
10.1101/GAD.1370505
P577
2005-12-01T00:00:00Z