Delineation of a cross-reactive idiotype on human autoantibodies with antibody against a synthetic peptide.
about
Cloning and sequence determination of a human rheumatoid factor light-chain geneCharacterization of human rheumatoid factors with seven antiidiotypes induced by synthetic hypervariable region peptides.Variable region diversity in human circulating antibodies specific for the capsular polysaccharide of Haemophilus influenzae type b. Preferential usage of two types of VH3 heavy chainsShared idiotypes and restricted immunoglobulin variable region heavy chain genes characterize murine autoantibodies of various specificities.Idiotypic markers of polyclonal B cell activation. Public idiotypes shared by monoclonal antibodies derived from patients with systemic lupus erythematosus or leprosy.Theoretical and practical aspects of antigenized antibodies.Complete protein sequences of the variable regions of the cloned heavy and light chains of a human anti-cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic family.Evolutionary origin of autoreactive determinants (autogens)Human antibody responses to bacterial antigens: studies of a model conventional antigen and a proposed model B cell superantigen.Expression of crossreactive idiotypes by human antibodies specific for the capsular polysaccharide of Hemophilus influenzae B.Characterization of an epibody. An antiidiotype that reacts with both the idiotype of rheumatoid factors (RF) and the antigen recognized by RF.Syngeneic antiidiotypic immune responses to a B cell lymphoma. Comparison between heavy chain hypervariable region peptides and intact Ig as immunogens.Synthetic peptides corresponding to third hypervariable region of human monoclonal IgM rheumatoid factor heavy chains define an immunodominant idiotypeHuman rheumatoid factor crossidiotypes. II. Primary structure-dependent crossreactive idiotype, PSL2-CRI, present on Wa monoclonal rheumatoid factors is present on Bla and other IgM kappa monoclonal autoantibodies.Human rheumatoid factor crossidiotypes. I. WA and BLA are heat-labile conformational antigens requiring both heavy and light chains.Complete amino acid sequences of variable regions of two human IgM rheumatoid factors, BOR and KAS of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segmentsStructure based antibody-like peptidomimetics.Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies.Genetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies.From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all.Towards a unified theory of immunoglobulin structure-function relations.Antibodies possessing multiple antigen specificities and exhibiting extensive idiotypic cross-reactivity.Functional and molecular studies of V genes expressed in autoantibodies.New concepts in autoimmunity.Perspectives on antigenicity and idiotypy.The use of defined peptides in characterizing idiotypes.Antigenicity and immunogenicity of antigenized antibodies. Studies on B and T cells.Dissection of the human antigammaglobulin idiotype system with monoclonal antibodies.Recognition by anti-Fab antibodies in rheumatoid arthritis of structure(s) widely distributed on human Fab molecules.
P2860
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P2860
Delineation of a cross-reactive idiotype on human autoantibodies with antibody against a synthetic peptide.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
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1984年學術文章
@zh-hant
name
Delineation of a cross-reactiv ...... y against a synthetic peptide.
@ast
Delineation of a cross-reactiv ...... y against a synthetic peptide.
@en
type
label
Delineation of a cross-reactiv ...... y against a synthetic peptide.
@ast
Delineation of a cross-reactiv ...... y against a synthetic peptide.
@en
prefLabel
Delineation of a cross-reactiv ...... y against a synthetic peptide.
@ast
Delineation of a cross-reactiv ...... y against a synthetic peptide.
@en
P2093
P2860
P356
P1476
Delineation of a cross-reactiv ...... y against a synthetic peptide.
@en
P2093
D A Carson
D Normansell
J G Karras
J H Vaughan
R A Houghten
P2860
P304
P356
10.1084/JEM.159.5.1502
P407
P577
1984-05-01T00:00:00Z