Early human IgH gene assembly in Epstein-Barr virus-transformed fetal B cell lines. Preferential utilization of the most JH-proximal D segment (DQ52) and two unusual VH-related rearrangements.
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A deletion map of the human immunoglobulin heavy chain variable regionChromosomal organization of the heavy chain variable region gene segments comprising the human fetal antibody repertoire.Preferential utilization of conserved immunoglobulin heavy chain variable gene segments during human fetal life.Population and family studies of three disease-related polymorphic genes in systemic lupus erythematosus.Germ line transcription of the immunoglobulin heavy chain locus directs production of mu chain without VDJ.The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidencSoma-to-germline feedback is implied by the extreme polymorphism at IGHV relative to MHC: The manifest polymorphism of the MHC appears greatly exceeded at Immunoglobulin loci, suggesting antigen-selected somatic V mutants penetrate Weismann's BarrieDevelopment of human antibody variable genes in systemic autoimmunity.Characterization of the immunoglobulin heavy chain complementarity determining region (CDR)-III sequences from human B cell precursor acute lymphoblastic leukemia cells.Comparative expression of adult and fetal V gene repertoires.Complete sequence of the genes encoding the VH and VL regions of low- and high-affinity monoclonal IgM and IgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient.Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: gene-segment use in mu and gamma transcripts.Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences.Autoantibodies encoded by the most Jh-proximal human immunoglobulin heavy chain variable region gene.Structure and expression of human germline VH transcriptsCoordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation.The biologic significance of human natural autoimmune responses: relationship to the germline, early immune and malignant B cell variable gene repertoire.Pathogenic anti-DNA antibodies in SLE: idiotypic families and genetic origins.Survival of the fetus: fetal B and T cell receptor repertoire development.Variable regions of a human anti-DNA antibody O-81 possessing lupus nephritis-associated idiotype.B-cell precursors differentiated from cord blood CD34+ cells are more immature than those derived from granulocyte colony-stimulating factor-mobilized peripheral blood CD34+ cells.Thymic selection of the human T cell receptor V beta repertoire in SCID-hu mice.Characterization of two human anti-DNA antibodies bearing the pathogenic idiotype 8.12.
P2860
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P2860
Early human IgH gene assembly in Epstein-Barr virus-transformed fetal B cell lines. Preferential utilization of the most JH-proximal D segment (DQ52) and two unusual VH-related rearrangements.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Early human IgH gene assembly ...... ual VH-related rearrangements.
@ast
Early human IgH gene assembly ...... ual VH-related rearrangements.
@en
type
label
Early human IgH gene assembly ...... ual VH-related rearrangements.
@ast
Early human IgH gene assembly ...... ual VH-related rearrangements.
@en
prefLabel
Early human IgH gene assembly ...... ual VH-related rearrangements.
@ast
Early human IgH gene assembly ...... ual VH-related rearrangements.
@en
P2093
P2860
P356
P1476
Early human IgH gene assembly ...... ual VH-related rearrangements.
@en
P2093
P2860
P304
P356
10.1084/JEM.169.4.1391
P407
P577
1989-04-01T00:00:00Z