Autoantibodies encoded by the most Jh-proximal human immunoglobulin heavy chain variable region gene.
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Third complementarity-determining region of mutated VH immunoglobulin genes contains shorter V, D, J, P, and N components than non-mutated genes.Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes.Sequence analysis of monoclonal antibodies derived from a patient with idiopathic thrombocytopenic purpura.Physical map of the 3' region of the human immunoglobulin heavy chain locus: clustering of autoantibody-related variable segments in one haplotypeIsolation of germinal centerlike events from human spleen RNA. Somatic hypermutation of a clonally related VH6DJH rearrangement expressed with IgM, IgG, and IgA.New roles for rheumatoid factor.Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable regionGeneration and analysis of clonal IgM- and IgG-producing human B cell lines expressing an anti-DNA-associated idiotype.Molecular basis of an autoantibody-associated restriction fragment length polymorphism that confers susceptibility to autoimmune diseasesAnalysis of the imperfect octamer-containing human immunoglobulin VH6 gene promoterBidirectional transcription from the human immunoglobulin VH6 gene promoter.Systematic analysis of sequences of anti-DNA antibodies--relevance to theories of origin and pathogenicity.Autoantibody activity and V gene usage by B-cell malignancies.The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection.Molecular approaches to the study of human B-cell and (auto)antibody repertoire generation and selection.Immortalisation of human antibody producing cells.VH-gene representation in autoantibodies reflects the normal human B-cell repertoire.A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles.Autoantibody selection and production in early human life.Molecular characterization of J558 genes encoding tight-skin mouse autoantibodies: identical heavy-chain variable genes code for antibodies with different specificities.Nucleotide sequence analysis of rheumatoid factors and polyreactive antibodies derived from patients with rheumatoid arthritis reveals diverse use of VH and VL gene segments and extensive variability in CDR-3.Superantigen properties of a human sialoprotein involved in gut-associated immunity.The human VH repertoire: a restricted set of VH genes may be the target of immune regulation.Expression and selection of murine antibody repertoires.Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven responseExtensive and selective mutation of a rearranged VH5 gene in human B cell chronic lymphocytic leukemia.Complete sequence of the genes encoding the VH and VL regions of low- and high-affinity monoclonal IgM and IgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient.VH genes of human autoantibodies.Examining the non-linear relationship between monoclonal antiphospholipid antibody sequence, structure and function.The early expression of some human autoantibody-associated heavy chain variable region genes is controlled by specific regulatory elements.Human heavy chain variable region gene diversity, organization, and expression.Autoantibodies and the fetal antibody repertoire.From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all.The biologic significance of human natural autoimmune responses: relationship to the germline, early immune and malignant B cell variable gene repertoire.High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans.Tight-skin mouse an experimental model for scleroderma.The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement.The role of autoreactivity in B cell selection.The role of antibodies to DNA in systemic lupus erythematosus--a review and introduction to an international workshop on DNA antibodies held in London, May 1996.Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus.
P2860
Q30993328-1BD6D4F1-5376-45B7-BC59-D3F278A8538AQ31131763-2350A348-2B7C-42C8-9E4E-5197C358AF17Q33392605-86B9C439-7D24-447F-A629-D36FFDD78F17Q33428825-2EBDFA7C-9761-4D45-9343-7D9D01D27D06Q33897378-C8C3322D-FCA0-4B6C-BF23-F5F2E95C7BD1Q34179855-8AE5BE74-D14E-436A-AB90-1B164EF486D1Q34183158-F20AA02F-7AF4-4975-9BD2-18CC7098D88EQ34186905-27B529DB-9E06-4F2E-87E0-6D4F29EC05F4Q34225507-04848A94-7F73-4D60-9A3A-892D16666CE0Q34809534-03260223-D99A-4224-B9C8-F3078C9B96EDQ34809613-60CAF9BE-F379-4890-B506-2F1BDDF27792Q35045892-8F63E1A0-FFA7-4829-9561-4AF793E25435Q35168545-C1C332C2-EB1C-4805-ACF6-5A2BB938BFFEQ35192913-22619DE0-A826-4C0C-BBCF-C1CFD241B3F7Q35235266-BF50E65F-0705-461C-8A39-1D1679510C70Q35237160-68A21C4B-BBD8-47E6-9081-F683D9C32B18Q35499760-1302243A-CB1E-4DC6-8B4B-A4A89742D64BQ35609941-48F0005A-2BCB-4D0B-BA02-DCCDBD3F956AQ35649405-9BCFED3D-2F01-4715-BB62-00969146C0F4Q35680386-369A63DA-DE8D-4A4A-940A-E9F71340B3E1Q35693031-2535686F-554F-430F-B7FF-688E98A5DEC1Q35750821-52C33316-56C5-485D-A41C-6DED634776DFQ36196150-5094F089-9D05-49E9-9EF8-E082F60FCF7EQ36196166-2CBF1514-51DF-46D8-8B9A-2E26A6553498Q36231063-23A18069-2A53-40F6-A057-111931D7E4C8Q36231831-EABD1B5C-ED3E-4D53-B03A-FFAEC3B011DEQ36248082-701B4B3E-AD15-4EC0-BD99-B858E94A98F3Q36687015-1F4B1096-DDCE-4F3B-BB6F-6380A505832BQ37283017-4A079E60-4FA6-436C-A5E7-163C21554DD9Q37816327-33CA2220-7087-4E9B-BBA5-E8A349A5C672Q37837335-D093A3F2-4857-49F7-94FD-E55EC2D1FB7BQ37837338-392A08C5-513B-4453-B78B-6B1E9D161E03Q37837345-9D3E4F5A-43AD-4709-82DF-DA2952951C9DQ37837361-DD36F234-154A-4E40-B53B-0F38DE48B0A8Q38711408-7F019392-94F1-493B-AE61-DC6724C87D49Q40393400-D23D6A07-C119-4369-95AE-E232E56DD210Q40626080-804502C3-7134-4B99-9E8A-296D1FFDF351Q41500775-AEFC856D-4830-4AEF-BDAE-6784391D4029Q41593886-85DB5D5A-9F08-4893-A972-3EA45F8299DBQ41697487-E8985919-317C-4649-A566-4DED8DC83A68
P2860
Autoantibodies encoded by the most Jh-proximal human immunoglobulin heavy chain variable region gene.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Autoantibodies encoded by the ...... vy chain variable region gene.
@ast
Autoantibodies encoded by the ...... vy chain variable region gene.
@en
type
label
Autoantibodies encoded by the ...... vy chain variable region gene.
@ast
Autoantibodies encoded by the ...... vy chain variable region gene.
@en
prefLabel
Autoantibodies encoded by the ...... vy chain variable region gene.
@ast
Autoantibodies encoded by the ...... vy chain variable region gene.
@en
P2093
P2860
P356
P1476
Autoantibodies encoded by the ...... vy chain variable region gene.
@en
P2093
F H Gmelig-Meyling
J H Van Es
T Logtenberg
P2860
P304
P356
10.1084/JEM.170.4.1347
P407
P577
1989-10-01T00:00:00Z