Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes
about
Targeting of NH2-terminal-processed microsomal protein to mitochondria: a novel pathway for the biogenesis of hepatic mitochondrial P450MT2Bimodal targeting of microsomal cytochrome P450s to mitochondria: implications in drug metabolism and toxicityCytochrome P450 regulation: the interplay between its heme and apoprotein moieties in synthesis, assembly, repair, and disposal.NH2-terminal substitutions of basic amino acids induce translocation across the microsomal membrane and glycosylation of rabbit cytochrome P450IIC2.Administration of 3-methylcholanthrene to rats increases the specific hybridizable mRNA coding for cytochrome P-450c.In vitro synthesis and posttranslational uptake of cytochrome c into isolated mitochondria: role of a specific addressing signal in the apocytochrome.Effect of phenobarbital on the level of translatable rat liver epoxide hydrolase mRNABimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals.Glycosylation does not determine segregation of viral envelope proteins in the plasma membrane of epithelial cellsDistribution and induction of cytochrome P-450 in rat liver nuclear envelope.Mechanisms for the incorporation of proteins in membranes and organelles.Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution.Synthesis and incorporation of myelin polypeptides into CNS myelin.Biosynthesis and processing of ribophorins in the endoplasmic reticulum.The influenza hemagglutinin insertion signal is not cleaved and does not halt translocation when presented to the endoplasmic reticulum membrane as part of a translocating polypeptide.Signals for the incorporation and orientation of cytochrome P450 in the endoplasmic reticulum membrane.Assembly in vitro of a spanning membrane protein of the endoplasmic reticulum: the E1 glycoprotein of coronavirus mouse hepatitis virus A59.Biogenesis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, an integral glycoprotein of the endoplasmic reticulumSignal recognition particle is required for co-translational insertion of cytochrome P-450 into microsomal membranesAnti-liver kidney microsome antibody recognizes a cytochrome P450 from the IID subfamily.Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulationFunctions of signal and signal-anchor sequences are determined by the balance between the hydrophobic segment and the N-terminal charge.Positive charges at the NH2 terminus convert the membrane-anchor signal peptide of cytochrome P-450 to a secretory signal peptideIdentification and localization of amino acid substitutions between two phenobarbital-inducible rat hepatic microsomal cytochromes P-450 by micro sequence analyses.Membrane topology and retention of microsomal aldehyde dehydrogenase in the endoplasmic reticulum.Cytochrome P-450 membrane signals.Emerging roles for brain drug-metabolizing cytochrome P450 enzymes in neuropsychiatric conditions and responses to drugs.Extensions of the signal hypothesis--sequential insertion model versus amphipathic tunnel hypothesis.An unusual TOM20/TOM22 bypass mechanism for the mitochondrial targeting of cytochrome P450 proteins containing N-terminal chimeric signals.Categorization of lipophilic xenobiotics by the enthalpic structure-function response of hepatic mixed-function oxidase.Compilation of published signal sequences.Purification and characterization of microsomal cytochrome P-450s.A short amino-terminal segment of microsomal cytochrome P-450 functions both as an insertion signal and as a stop-transfer sequence.Determination of the membrane topology of the phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4 using site-specific antibodies.Three immunoidentical cytochromes P-450 from liver microsomes of phenobarbital-treated rats.Characterization of translation products of the polyadenylated RNA of free and membrane-bound polyribosomes of rat forebrain.Induction by phenobarbital of the mRNA for a specific variant of rat liver microsomal cytochrome P-450.The microsomal epoxide hydrolase has a single membrane signal anchor sequence which is dispensable for the catalytic activity of this protein.Biosynthesis of intestinal microvillar proteins. Processing of aminopeptidase N by microsomal membranes.Measurement of the metabolism of cytochrome P-450 in cultured hepatocytes by a quantitative and specific immunochemical method.
P2860
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P2860
Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes
description
1980 nî lūn-bûn
@nan
1980年の論文
@ja
1980年学术文章
@wuu
1980年学术文章
@zh-cn
1980年学术文章
@zh-hans
1980年学术文章
@zh-my
1980年学术文章
@zh-sg
1980年學術文章
@yue
1980年學術文章
@zh
1980年學術文章
@zh-hant
name
Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes
@ast
Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes
@en
type
label
Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes
@ast
Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes
@en
prefLabel
Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes
@ast
Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes
@en
P2093
P2860
P356
P1476
Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes
@en
P2093
P2860
P304
P356
10.1073/PNAS.77.2.965
P407
P577
1980-02-01T00:00:00Z