Histone acetylation at the human beta-globin locus changes with developmental age.
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Current and future alternative therapies for beta-thalassemia majorFetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathiesEnvironmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegenerationNuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.The distinctive roles of erythroid specific activator GATA-1 and NF-E2 in transcription of the human fetal γ-globin genes.Epigenetic modifications and chromosome conformations of the beta globin locus throughout development.Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration.Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells.Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemiaHemoglobin research and the origins of molecular medicine.Epigenetics of beta-globin gene regulationDifferential epigenetic modifications of histones at the myosin heavy chain genes in fast and slow skeletal muscle fibers and in response to muscle unloadingInhibition of histone acetylation by curcumin reduces alcohol-induced fetal cardiac apoptosis.A spectrum of gene regulatory phenomena at mammalian beta-globin gene loci.Reawakening fetal hemoglobin: prospects for new therapies for the β-globin disorders.The higher structure of chromatin in the LCR of the beta-globin locus changes during development.Dynamics of alpha-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34(+) cells in culture.Developmentally regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human beta-globin locus.Complex developmental patterns of histone modifications associated with the human beta-globin switch in primary cells.Evidence for a bigenic chromatin subdomain in regulation of the fetal-to-adult hemoglobin switch.Fetal haemoglobin induction in sickle cell disease.
P2860
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P2860
Histone acetylation at the human beta-globin locus changes with developmental age.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Histone acetylation at the human beta-globin locus changes with developmental age.
@ast
Histone acetylation at the human beta-globin locus changes with developmental age.
@en
type
label
Histone acetylation at the human beta-globin locus changes with developmental age.
@ast
Histone acetylation at the human beta-globin locus changes with developmental age.
@en
prefLabel
Histone acetylation at the human beta-globin locus changes with developmental age.
@ast
Histone acetylation at the human beta-globin locus changes with developmental age.
@en
P2093
P2860
P1433
P1476
Histone acetylation at the human beta-globin locus changes with developmental age.
@en
P2093
George Stamatoyannopoulos
Ping Xiang
Qiliang Li
Wenxuan Yin
Xiangdong Fang
P2860
P304
P356
10.1182/BLOOD-2007-05-091256
P407
P577
2007-09-19T00:00:00Z