Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice
about
Multiple immuno-regulatory defects in type-1 diabetesType I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune diseaseDissecting the role of CD4+ T cells in autoimmune diabetes through the use of TCR transgenic mice.Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis.Interleukin-10 increases Th1 cytokine production and cytotoxic potential in human papillomavirus-specific CD8(+) cytotoxic T lymphocytes.The application of gene therapy in autoimmune diseases.Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice.Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription.In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice.Progress in understanding autoimmune exocrinopathy using the non-obese diabetic mouse: an update.Immunotherapy of type 1 diabetes: lessons for other autoimmune diseases.Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage: Scavenging effect against reactive oxygen species.Carcinogenicity testing of IL-10: principles and practicalities.Current knowledge of Japanese type 1 diabetic syndrome.Cytokine-based immunointervention in the treatment of autoimmune diseases.Interleukin 10 treatment for rheumatoid arthritisCurrent status of gene delivery and gene therapy in lacrimal gland using viral vectors.Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β.Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy.Enhancement of anti-murine colon cancer immunity by fusion of a SARS fragment to a low-immunogenic carcinoembryonic antigen.Beta cell apoptosis in T cell-mediated autoimmune diabetes.IP-10 and type 1 diabetes: a question of time and location.Antigen-specific induction of regulatory T cells for type 1 diabetes therapy.CD4+ beta islet cell-reactive T cell clones that suppress autoimmune diabetes in nonobese diabetic mice.Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors.Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes.IL-10 is necessary and sufficient for autoimmune diabetes in conjunction with NOD MHC homozygosityTreatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells.alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.Effect of PRX-1 Downregulation in the Type 1 Diabetes MicroenvironmentRodent models for investigating the dysregulation of immune responses in type 1 diabetes.Dietary flavonol epicatechin prevents the onset of type 1 diabetes in nonobese diabetic mice.Targeting regulatory T cells in the treatment of type 1 diabetes mellitus.Local expression of immunoregulatory IL-12p40 gene prolonged syngeneic islet graft survival in diabetic NOD mice.Viruses, cytokines, antigens, and autoimmunity.Checkpoints in the progression of autoimmune disease: lessons from diabetes models.Plant-made pharmaceuticals for the prevention and treatment of autoimmune diseases: where are we?Treg and CTLA-4: two intertwining pathways to immune tolerance.B1 cells promote pancreas infiltration by autoreactive T cells.Immunomodulation by helminths: Similar impact on type 1 and type 2 diabetes?
P2860
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P2860
Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Production of interleukin 10 b ...... ells in nonobese diabetic mice
@ast
Production of interleukin 10 b ...... ells in nonobese diabetic mice
@en
type
label
Production of interleukin 10 b ...... ells in nonobese diabetic mice
@ast
Production of interleukin 10 b ...... ells in nonobese diabetic mice
@en
prefLabel
Production of interleukin 10 b ...... ells in nonobese diabetic mice
@ast
Production of interleukin 10 b ...... ells in nonobese diabetic mice
@en
P2093
P2860
P356
P1476
Production of interleukin 10 b ...... ells in nonobese diabetic mice
@en
P2093
P2860
P304
P356
10.1084/JEM.179.4.1379
P407
P577
1994-04-01T00:00:00Z