Beta cell apoptosis in T cell-mediated autoimmune diabetes. - Wikidata - awgldk - TriplyDB

Beta cell apoptosis in T cell-mediated autoimmune diabetes.

Beta cell apoptosis in T cell-mediated autoimmune diabetes.

http://www.wikidata.org/entity/Q35905815

about

Assay for high glucose-mediated islet cell sensitization to apoptosis induced by streptozotocin and cytokines Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis.Specific silencing of the REST target genes in insulin-secreting cells uncovers their participation in beta cell survival Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis Adeno-associated virus vector mediated gene transfer to pancreatic beta cells.Inflammatory blockade improves human pancreatic islet function and viability.Investigating the role of T-cell avidity and killing efficacy in relation to type 1 diabetes prediction.Low-dose radiation and its clinical implications: diabetes.Type I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune disease Antigen presentation pathways for immunity to islet transplants. Relevance to immunoisolation.Tumor necrosis factor-alpha and the progression of diabetes in non-obese diabetic mice.Dissecting the role of CD4+ T cells in autoimmune diabetes through the use of TCR transgenic mice.Role of autoreactive CD8+ T cells in organ-specific autoimmune diseases: insight from transgenic mouse models.Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis.Different modes of pathogenesis in T-cell-dependent autoimmunity: clues from two TCR transgenic systems.Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes T cell receptor gene usage in autoimmune diabetes.Apoptosis in human autoimmune diseases.The pathogenicity of self-antigen decreases at high levels of autoantigenicity: a computational approach.Cutting edge: merocytic dendritic cells break T cell tolerance to beta cell antigens in nonobese diabetic mouse diabetes.Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner.Unraveling the contribution of pancreatic beta-cell suicide in autoimmune type 1 diabetes.Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes TGF-beta signaling is required for the function of insulin-reactive T regulatory cells Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone.Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models.Caspase-3 is involved in IFN-γ- and TNF-α-mediated MIN6 cells apoptosis via NF-κB/Bcl-2 pathway.Novel actions of IGFBP-3 on intracellular signaling pathways of insulin-secreting cells.Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma.Oxidative stress and redox modulation potential in type 1 diabetes.The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death.Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice Hepatic insulin gene therapy in insulin-dependent diabetes mellitus.NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice Induction of protective genes leads to islet survival and function.Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice.Can CD44 Be a Mediator of Cell Destruction? The Challenge of Type 1 Diabetes.Gene Co-Expression Network Analysis for Identifying Modules and Functionally Enriched Pathways in Type 1 Diabetes.Apoptosis of human islet cells by cytokines.

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Beta cell apoptosis in T cell-mediated autoimmune diabetes.

http://www.wikidata.org/entity/Q35905815

description

1997 nî lūn-bûn

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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1997年论文

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1997年论文

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name

Beta cell apoptosis in T cell-mediated autoimmune diabetes.

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Beta cell apoptosis in T cell-mediated autoimmune diabetes.

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Beta cell apoptosis in T cell-mediated autoimmune diabetes.

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Beta cell apoptosis in T cell-mediated autoimmune diabetes.

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Beta cell apoptosis in T cell-mediated autoimmune diabetes.

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Beta cell apoptosis in T cell-mediated autoimmune diabetes.

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Proceedings of the National Academy of Sciences of the United States of America

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Beta cell apoptosis in T cell-mediated autoimmune diabetes.

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H L Hanson

http://www.w3.org/2001/XMLSchema#string

J D Katz

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M O Kurrer

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S V Pakala

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P2860

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

The Fas death factor

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.

In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice.

Pancreatic islet-specific T-cell clones from nonobese diabetic mice

Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide

Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice

Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice.

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94

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19288

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