Mutational analysis of an autoantibody: differential binding and pathogenicity. - Wikidata - awgldk - TriplyDB

Mutational analysis of an autoantibody: differential binding and pathogenicity.

Mutational analysis of an autoantibody: differential binding and pathogenicity.

http://www.wikidata.org/entity/Q36363653

about

The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity.Mechanisms of Kidney Injury in Lupus Nephritis - the Role of Anti-dsDNA Antibodies A model for lupus brain disease Mesangial cell-specific antibodies are central to the pathogenesis of lupus nephritis The double edged sword of the immune response: mutational analysis of a murine anti-pneumococcal, anti-DNA antibody Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response Antibodies and brain disease: a convergence of immunology and physiology.The antigenic properties of bacterial DNA in normal and aberrant immunity.Antibodies and the Brain: Lessons from Lupus.Identification of a lipid peroxidation product as the source of oxidation-specific epitopes recognized by anti-DNA autoantibodies.Immunity and behavior: antibodies alter emotion Lessons from an anti-DNA autoantibody.Systematic analysis of sequences of anti-DNA antibodies--relevance to theories of origin and pathogenicity.Molecular expression systems for anti-DNA antibodies--1.Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity.Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells.Human lupus autoantibodies against NMDA receptors mediate cognitive impairment.Brain-reactive antibodies and disease.Anti-dsDNA, anti-Sm antibodies, and the lupus anticoagulant: significant factors associated with lupus nephritis Peptide inhibition of glomerular deposition of an anti-DNA antibody.Light chain usage in anti-double-stranded DNA B cell subsets: role in cell fate determination Pathogenic profiles and molecular signatures of antinuclear autoantibodies rescued from NZM2410 lupus mice The constant region contributes to the antigenic specificity and renal pathogenicity of murine anti-DNA antibodies.Ligand recognition by murine anti-DNA autoantibodies. II. Genetic analysis and pathogenicity.Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway.Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in patients with lupus nephritis: a prospective longitudinal study Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease Glomerular antibodies in lupus nephritis.NMDA Receptor Activity in Neuropsychiatric Disorders.Molecular determinants of polyreactive antibody binding: HCDR3 and cyclic peptides.Autoreactive responses to an environmental factor: 1. phthalate induces antibodies exhibiting anti-DNA specificity.Anti-nuclear antibody reactivity in lupus may be partly hard-wired into the primary B-cell repertoire Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.Molecular hallmarks of anti-chromatin antibodies associated with the lupus susceptibility locus, Sle1.Anti-laminin reactivity and glomerular immune deposition by in vitro recombinant antibodies.Amending HIV Drugs: A Novel Small-Molecule Approach To Target Lupus Anti-DNA Antibodies Microbial antigens can elicit autoantibody production. A potential pathway to autoimmune disease.The role of antibodies to DNA in systemic lupus erythematosus--a review and introduction to an international workshop on DNA antibodies held in London, May 1996.PDTC attenuate LPS-induced kidney injury in systemic lupus erythematosus-prone MRL/lpr mice.

P2860

Q24798707-5E8F03F1-E758-4CDB-9D29-934E5C60345B Q24812196-67B38FCD-CFBB-4091-BD97-C1B7D7C14513 Q26781272-E102D349-0C43-4B55-A70E-5D2770DECCE7 Q26824461-BCC78FB5-B034-48AF-AB3C-A993548F7C76 Q26991887-3C6A0B82-20F5-4FA8-85D8-16DA6E58322C Q28378842-89AEBF2C-B019-4045-8AC3-D7CE1B7BC720 Q28384306-97396BD8-0BC9-497A-BE9F-BD86BC7143AB Q33267001-92751D19-15EB-4E5A-B60F-CDA9E739AAE4 Q34005461-8B41C661-A4F4-49F7-8C1A-E0503F88E177 Q34201906-01549E50-FF84-4FC5-96B3-94F0D59BEF77 Q34232022-94342CD3-522C-4C92-8494-4F279D990692 Q34270963-B8FCCBAD-8E17-436E-8533-58D0D236D298 Q35013745-6888D854-A7BE-48C6-8C22-AFD31B47DC97 Q35045892-C394D9A7-0CF4-4ECE-A348-9BAD6647EBA4 Q35045897-5A9F105A-9F44-497D-92F9-BBBA0B89A94D Q35064255-9BA38F6A-FCAC-4EB4-8D73-EBA19E526BB8 Q35079469-117961DE-2BAE-4B89-9942-849FAF251045 Q35225108-F97CBB17-1AC7-45FD-8E2E-35F3FCE3534B Q35458567-BE1A6AD5-4F09-4250-B308-3B9EFD4D559B Q35552732-6D0D4DFC-7A3B-491F-B44B-398EBC8B59F2 Q36029509-C6678030-567E-43EE-B778-C22B48024C37 Q36377073-5037AAF4-CF30-41E1-9B60-461C73F4F833 Q36399144-C90E80DA-31D3-45BA-BBDC-4046943D0323 Q36850723-0F8AF079-B6F6-4A9A-B8BB-819E2716F9EB Q37353912-91C2A638-750B-4B0F-9FD9-DF4FAC93AAAD Q37409260-F0DD1A7A-CB12-4CE3-8AD6-E47312DACF6D Q37453929-9945724F-C126-4CEC-B3AB-CFC3B895947C Q37708458-5C16E558-2DBF-4E59-BA1A-392CEC00459C Q37736310-AD69CAF5-4EB2-4A56-9F78-1441794E0DAE Q38114881-C5EA030D-6EA5-4259-8C5B-D9A9D153E4B9 Q38317267-53FF775B-09F4-4DB3-AFDE-CBB51F589ED6 Q38347732-43C3AB7C-24DD-4C1B-AA54-02051BB05E6A Q38492863-9E0968D4-C2B1-460B-915C-F6369988DE6B Q39809953-31401638-F67A-4FA5-B2B8-5F2029FCCAE1 Q41089309-6067CF4B-0F55-453C-9643-2F97CA10105D Q41136316-23EC7963-E366-4CA2-848F-A4E076DDC322 Q41406224-7CE81EB3-755B-4003-AFC3-1AE37FBE2824 Q41500879-A8DF3C69-B756-42AD-9EF0-4EDE313BE222 Q41593886-DDBF0AA9-3A83-4D99-9385-3F610D7ACB7C Q43827750-5D0559D7-E4AB-4C13-9392-DD620F2FC14E

P2860

Mutational analysis of an autoantibody: differential binding and pathogenicity.

http://www.wikidata.org/entity/Q36363653

description

1994 nî lūn-bûn

@nan

1994年の論文

@ja

1994年学术文章

@wuu

1994年学术文章

@zh-cn

1994年学术文章

@zh-hans

1994年学术文章

@zh-my

1994年学术文章

@zh-sg

1994年學術文章

@yue

1994年學術文章

@zh

1994年學術文章

@zh-hant

name

Mutational analysis of an autoantibody: differential binding and pathogenicity.

@ast

Mutational analysis of an autoantibody: differential binding and pathogenicity.

@en

type

label

Mutational analysis of an autoantibody: differential binding and pathogenicity.

@ast

Mutational analysis of an autoantibody: differential binding and pathogenicity.

@en

prefLabel

Mutational analysis of an autoantibody: differential binding and pathogenicity.

@ast

Mutational analysis of an autoantibody: differential binding and pathogenicity.

@en

P1433

Q36363653-AC4DBBE0-1A10-4F67-AFBE-400481C423AB

P1476

Q36363653-CEF5A760-F82E-48D8-A231-453FC8650F89

P2093

Q36363653-125BB293-3EEF-4ED7-8A42-1A69BE176FFE

Q36363653-19823156-2965-44D7-AD6F-DF9EA54A0F13

Q36363653-D85622D4-134D-46DF-A7B4-113B211D25C3

P2860

Q36363653-059A1D04-4DB9-4E93-953E-6460B0B1C6FB

Q36363653-065D36FE-81BE-4CE5-883B-5E49A49F7ADC

Q36363653-1A87DE4B-B7B7-48E8-8041-B42D17DBD9B0

Q36363653-287D39C0-56B0-42FD-A0E7-3AA7E91EB982

Q36363653-619932A8-C0E1-4E4B-A397-730312B69D1C

Q36363653-6AA71C63-38BE-432E-B6D1-9ADFB4C30A85

Q36363653-6D8079AF-542B-4630-95CF-2DCB4B1C61CD

Q36363653-7DF33AE3-BC0D-49F1-BA12-375EA2C62CBD

Q36363653-89D3B7CF-20BD-4F69-A685-F4B017604438

Q36363653-962B35EC-3AB2-4C18-9853-F3FD72C18A56

P304

Q36363653-E220A20E-18F5-420F-B894-06790EB7A010

P31

Q36363653-99C64D84-31D0-4D8C-BE1A-2406A25FEE98

P356

Q36363653-6ADEFDAA-2336-4005-805C-C2630534BB0A

P407

Q36363653-CAFC5E32-7379-4BE9-84BD-7532EFC7A433

P433

Q36363653-2A020A6B-2039-44A1-9F2E-C2AB9EC0D018

P478

Q36363653-BF379660-9105-4421-9A01-8C6CE749F31B

P577

Q36363653-BB35B7A2-E904-4D2E-94F5-1BC7822262BC

P5875

Q36363653-7997BC6D-2490-4323-85B6-80F60B0102D9

P698

Q36363653-387E4AD4-45D6-4D7D-90AB-11C9BB6AF80B

P921

Q36363653-50972558-2558-4B34-BB8E-D5379F8332E2

P932

Q36363653-78730225-CE4B-4B18-B3B5-1B873F9EFE05

P356

P1433

Journal of Experimental Medicine

P1476

Mutational analysis of an autoantibody: differential binding and pathogenicity.

@en

P2093

B Diamond

http://www.w3.org/2001/XMLSchema#string

J B Katz

http://www.w3.org/2001/XMLSchema#string

W Limpanasithikul

http://www.w3.org/2001/XMLSchema#string

P2860

An autoantibody to single-stranded DNA: comparison of the three-dimensional structures of the unliganded Fab and a deoxynucleotide-Fab complex

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

Variable region framework differences result in decreased or increased affinity of variant anti-digoxin antibodies.

Somatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 mice

Structural correlates of high antibody affinity: three engineered amino acid substitutions can increase the affinity of an anti-p-azophenylarsonate antibody 200-fold

Molecular characterization of a somatically mutated anti-DNA antibody bearing two systemic lupus erythematosus-related idiotypes

Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism.

Sequence-specific recognition of double helical nucleic acids by proteins.

A novel class of anti-DNA antibodies identified in BALB/c mice.

Characterization of somatically mutated S107 VH11-encoded anti-DNA autoantibodies derived from autoimmune (NZB x NZW)F1 mice.

P304

925-932

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.180.3.925

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

180

http://www.w3.org/2001/XMLSchema#string

P577

1994-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

15135489

http://www.w3.org/2001/XMLSchema#string

P698

8064241

http://www.w3.org/2001/XMLSchema#string

P921

P932

2191646

http://www.w3.org/2001/XMLSchema#string