Structural correlates of high antibody affinity: three engineered amino acid substitutions can increase the affinity of an anti-p-azophenylarsonate antibody 200-fold
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The structural basis of repertoire shift in an immune response to phosphocholineEvolutionary transition pathways for changing peptide ligand specificity and structureStructure of the male determinant factor for Brassica self-incompatibilityGroove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked GlycanImproved affinity of a human anti-Entamoeba histolytica Gal/GalNAc lectin Fab fragment by a single amino acid modification of the light chainSingle-chain variable fragment antibodies against the neural adhesion molecule CHL1 (close homolog of L1) enhance neurite outgrowth.Optimality of mutation and selection in germinal centers.Protein evolution on partially correlated landscapes.scFv antibody: principles and clinical applicationMutational analysis of an autoantibody: differential binding and pathogenicity.Altering the antibody repertoire via transgene homologous recombination: evidence for global and clone-autonomous regulation of antigen-driven B cell differentiation.Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen.Tracing the development of single memory-lineage B cells in a highly defined immune response.Virus neutralization by germ-line vs. hypermutated antibodies.Antibody recognition of carbohydrate epitopes†.Oligonucleotide-directed mutagenesis of antibody combining sites.The structural repertoire of the human V kappa domainAntibody production in the baculovirus expression system.Increased antibody affinity and specificity by codon-based mutagenesis.Differences in antigen-binding affinity caused by a single amino acid substitution in the variable region of the heavy chain.A human anti-insulin IgG autoantibody apparently arises through clonal selection from an insulin-specific "germ-line" natural antibody template. Analysis by V gene segment reassortment and site-directed mutagenesis.Affinity of anti-HBs antibody after hepatitis B vaccination.
P2860
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P2860
Structural correlates of high antibody affinity: three engineered amino acid substitutions can increase the affinity of an anti-p-azophenylarsonate antibody 200-fold
description
1990 nî lūn-bûn
@nan
1990 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Structural correlates of high ...... enylarsonate antibody 200-fold
@ast
Structural correlates of high ...... enylarsonate antibody 200-fold
@en
type
label
Structural correlates of high ...... enylarsonate antibody 200-fold
@ast
Structural correlates of high ...... enylarsonate antibody 200-fold
@en
prefLabel
Structural correlates of high ...... enylarsonate antibody 200-fold
@ast
Structural correlates of high ...... enylarsonate antibody 200-fold
@en
P2860
P356
P1476
Structural correlates of high ...... enylarsonate antibody 200-fold
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.12.4814
P407
P577
1990-06-01T00:00:00Z