Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
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How the fanconi anemia pathway guards the genomeFanconi anemia genes are highly expressed in primitive CD34+ hematopoietic cellsUpdate of the human and mouse Fanconi anemia genesLearning from a paradox: recent insights into Fanconi anaemia through studying mouse modelsEpithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout miceThe Fanconi anaemia/BRCA pathwayA novel ubiquitin ligase is deficient in Fanconi anemiaCharacterization, expression and complex formation of the murine Fanconi anaemia gene product FancgInteraction of FANCD2 and NBS1 in the DNA damage responseMouse models of Fanconi anemiaCellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insightsFancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in miceLoss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouseThe Fanconi anemia pathway and ubiquitinCytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cellsMouse models of human familial cancer syndromes.Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination.An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis.Null mutations in human and mouse orthologs frequently result in different phenotypes.Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.Intraesophageal manganese superoxide dismutase-plasmid liposomes ameliorates novel total-body and thoracic radiation sensitivity of NOS1-/- mice.The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair.Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.Mouse models of inherited cancer syndromesTumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice.Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg.The phenotype of FancB-mutant mouse embryonic stem cells.Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells.Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated.Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma.Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- miceFanconi anemia A is a nucleocytoplasmic shuttling molecule required for gonadotropin-releasing hormone (GnRH) transduction of the GnRH receptorDisrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies.Survival of the fittest: in vivo selection and stem cell gene therapyFancb deficiency impairs hematopoietic stem cell function.Transgenic rescue of ataxia mice reveals a male-specific sterility defect.CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumorsMesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo.
P2860
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P2860
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
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2001 nî lūn-bûn
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2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
@ast
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
@en
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
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Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
@ast
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
@en
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
@nl
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Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
@ast
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
@en
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
@nl
P2093
P3181
P1433
P1476
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9
@en
P2093
A D D'Andrea
R Montes De Oca
P304
P3181
P356
10.1182/BLOOD.V98.12.3435
P407
P577
2001-12-01T00:00:00Z