The Ets protein Spi-B is expressed exclusively in B cells and T cells during development. - Wikidata - awgldk - TriplyDB

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

http://www.wikidata.org/entity/Q36366999

about

Assembly requirements of PU.1-Pip (IRF-4) activator complexes: inhibiting function in vivo using fused dimers The ETS transcription factor Spi-B is required for human plasmacytoid dendritic cell development Regulation of lymphocyte apoptosis by interferon regulatory factor 4 (IRF-4)SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1 Spi-B can functionally replace PU.1 in myeloid but not lymphoid development Differentiation of human fetal multipotential neural progenitor cells to astrocytes reveals susceptibility factors for JC virus.Spi-C, a novel Ets protein that is temporally regulated during B lymphocyte development.Prf, a novel Ets family protein that binds to the PU.1 binding motif, is specifically expressed in restricted stages of B cell development.PU.1 is a lineage-specific regulator of tyrosine phosphatase CD45.Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B.PU.1 and Haematopoietic Cell Fate: Dosage Matters Transcription factor Spi-B binds unique sequences present in the tandem repeat promoter/enhancer of JC virus and supports viral activity Expression and function of Ets transcription factors in mammalian development: a regulatory network.EBV-encoded LMP1 upregulates Igκ 3'enhancer activity and Igκ expression in nasopharyngeal cancer cells by activating the Ets-1 through ERKs signaling.The generation of antibody-secreting plasma cells.A new, lineage specific, autoup-regulation mechanism for human glucocorticoid receptor gene expression in 697 pre-B-acute lymphoblastic leukemia cells.Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria.Do lampreys have lymphocytes? The Spi evidence.Nfkb1 activation by the E26 transformation-specific transcription factors PU.1 and Spi-B promotes Toll-like receptor-mediated splenic B cell proliferation.Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling.JC virus promoter/enhancers contain TATA box-associated Spi-B-binding sites that support early viral gene expression in primary astrocytes.Human thymus contains IFN-alpha-producing CD11c(-), myeloid CD11c(+), and mature interdigitating dendritic cells Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma.Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancer Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression.The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells.Quercetin suppresses immune cell accumulation and improves mitochondrial gene expression in adipose tissue of diet-induced obese mice.IRF4: Immunity. Malignancy! Therapy?Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors.The diverse roles of IRF4 in late germinal center B-cell differentiation.Host cell virus entry mechanisms enhance anti-JCV-antibody switch in natalizumab-treated multiple sclerosis patients.Modulation of Ets-1 expression in B lymphocytes is dependent on the antigen receptor-mediated activation signals and cell cycle status.Use of recombinant cell-permeable small peptides to modulate glucocorticoid sensitivity of acute lymphoblastic leukemia cells MiR-126: a novel route for natalizumab action?The Ets factors PU.1 and Spi-B regulate the transcription in vivo of P2Y10, a lymphoid restricted heptahelical receptor.Polyomavirus JC reactivation and noncoding control region sequence analysis in pediatric Crohn's disease patients treated with infliximab.

P2860

Q24533589-DFDB2BAA-0EC2-41D2-9630-B5EADD63EFDD Q24647527-0D36DCE6-571D-4327-838B-57DE31ED5203 Q24673747-0788D364-3274-46AA-9F88-378B4F8CB035 Q28119191-AFC8B15D-D8B7-4140-A439-670A02AA8A11 Q28585427-0D69FB4B-13DD-4BD3-8428-85868B07CE93 Q30539642-9CBBA300-6C06-4792-85D2-094F97221215 Q30667280-98DF8285-699C-4C0C-865B-6D1837A11C81 Q30760665-65D2F99E-AB52-4B4D-AD2C-CF6BE80A4067 Q31677523-91CF1DEA-5934-403E-9575-CE5D9745843F Q33887829-1DB70E29-9FBB-4AD9-ABBB-081E780358A7 Q34028171-86EE5A0D-A2E9-4442-A5BB-90BB18F649EA Q34136900-B1BF2CDC-9926-40A8-BF32-127D5EE452E8 Q34139379-C3E102A9-5426-49EA-8917-C351170B0AE9 Q34187244-CB1BF8CD-79D6-470E-9CA5-123F933E11F6 Q34463732-E642CC6A-2AAD-4834-8156-8B5E757E0F22 Q34548873-7878CE59-3476-4EE9-BC31-0F97158B7A02 Q34617317-E51BBFA7-C08D-4696-B4D6-C8565D079AAE Q35159905-A57018DF-BCC1-45CC-BD11-FAE5E101F376 Q35288509-AF51C22C-A030-457E-911E-A67B518A7A5E Q35688012-28F8C2BD-A3D1-4599-8F6C-EEC89E909919 Q35960553-67087B02-207B-4C2F-B1CB-80076A3054CE Q36017166-7EC4DAAF-658E-49A8-B2A5-2176F7139EEF Q36267192-6F6392F7-5A5E-4027-A0CC-C010376D1578 Q36376708-B0C23853-78C1-4248-A490-E466E10A6DEF Q36843718-CDE0E7BC-55AB-4FD9-AD68-D81D21B46899 Q36991688-01A21E00-ABF1-4429-A64A-40DF187130E7 Q37337265-6637E694-4EE4-4A2F-9551-AFE4B3026638 Q37454043-9C588CD5-0FAC-46F4-9EF2-3F3D7730302D Q37592367-6224B930-62A6-4EE9-BD55-1BBF5EFC5E4B Q37636535-7E8269C8-FA26-44F4-B5FD-FC71FF4D3586 Q38002486-C5BCA0C8-32CC-4C81-B2AC-221783836274 Q38868240-C993D5D3-B22B-4882-8A51-19DF44A876CB Q39231732-BD54C46D-5230-4301-9046-5AA8DDEC3EDB Q39657220-334B301D-D3CF-4DD2-8137-723BA293354E Q42233577-3E5EB868-2891-42FF-8FE0-835805D29FC0 Q42808627-E8AC7229-A8D5-4167-A116-603766BEE019 Q54374397-FAF1B388-BAF0-4A2F-A771-BD09BAB6F123

P2860

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

http://www.wikidata.org/entity/Q36366999

description

1996 nî lūn-bûn

@nan

1996年の論文

@ja

1996年学术文章

@wuu

1996年学术文章

@zh-cn

1996年学术文章

@zh-hans

1996年学术文章

@zh-my

1996年学术文章

@zh-sg

1996年學術文章

@yue

1996年學術文章

@zh

1996年學術文章

@zh-hant

name

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

@ast

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

@en

type

label

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

@ast

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

@en

prefLabel

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

@ast

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

@en

P1433

Q36366999-8019392F-B6A1-4720-BE9E-FD1546CC866E

P1476

Q36366999-B44FE816-DE93-4958-8D9B-8473B61C8C05

P2093

Q36366999-0AE3331B-416B-46B4-9A98-D05393B92688

Q36366999-0DEEEF64-AD33-423B-ABBD-7A603D037437

Q36366999-1B542578-5DF1-4203-9175-479434F4A94E

Q36366999-3C19A02F-B21B-40B8-A4EA-40B77D30E01A

Q36366999-52B16032-49B9-45A9-A80A-DB25966752B3

Q36366999-9C63629D-7EEB-4F8E-866E-EB1B0FBFC357

P2860

Q36366999-01CF4E2F-B5B0-4450-897C-06F5DF5AEF20

Q36366999-06FC1FCD-D727-4454-9D00-DCD08BE4D100

Q36366999-13F5BAFC-0E80-4D64-8CDB-05F99154A2DC

Q36366999-23361062-D815-4C46-A980-C4785D41DBE3

Q36366999-2A40C52D-6EFD-4BDA-8DC6-B57988574A0A

Q36366999-3663A720-7C68-4100-8181-DF5D9164A036

Q36366999-376ECB5E-06DB-41E5-8D5E-6D840EB97C38

Q36366999-388735A6-2983-4473-9282-C85AA1107094

Q36366999-4F91DC14-2A88-406F-B3C5-DA308E9A8460

Q36366999-50A3CC4A-461B-44A1-B0B0-8A69F41831FA

P304

Q36366999-148A5E80-4502-421D-8B61-31672EC0CA9D

P31

Q36366999-3DAF714B-0191-44AE-9334-244A50C76458

P356

Q36366999-87E7F5F9-BEBD-4EFD-8B26-3C191CF4AA7C

P407

Q36366999-82E36C45-D573-408B-9A53-F8DAC41C0719

P433

Q36366999-2525D6BD-2DC2-4E43-899E-DCF858ADCEEE

P478

Q36366999-9FF598DA-3C2F-49DF-B5A1-BFF45B4D5D0A

P577

Q36366999-F323BBB7-BE13-4427-B342-8674D2ACB781

P5875

Q36366999-AA8F8E6C-A403-46ED-A8DF-7EA385C4E144

P698

Q36366999-9DBEC78D-AD07-4B52-976D-66023BDA2C1A

P932

Q36366999-55D14268-44ED-49AC-887B-0641FAC9E345

P356

P1433

Journal of Experimental Medicine

P1476

The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

@en

P2093

B S Cobb

http://www.w3.org/2001/XMLSchema#string

G H Su

http://www.w3.org/2001/XMLSchema#string

H M Chen

http://www.w3.org/2001/XMLSchema#string

H S Ip

http://www.w3.org/2001/XMLSchema#string

M C Simon

http://www.w3.org/2001/XMLSchema#string

M M Lu

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

Rescue of erythroid development in gene targeted GATA-1- mouse embryonic stem cells

Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene

The Ikaros gene is required for the development of all lymphoid lineages

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

P304

203-214

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.184.1.203

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

184

http://www.w3.org/2001/XMLSchema#string

P577

1996-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

277548346

http://www.w3.org/2001/XMLSchema#string

P698

8691135

http://www.w3.org/2001/XMLSchema#string

P932

2192671

http://www.w3.org/2001/XMLSchema#string