Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands
about
Detection and characterization of cellular immune responses using peptide-MHC microarraysStructural Basis of Specificity and Cross-Reactivity in T Cell Receptors Specific for Cytochrome c-I-EDefinition of agonists and design of antagonists for alloreactive T cell clones using synthetic peptide libraries.Minimal peptide length requirements for CD4(+) T cell clones--implications for molecular mimicry and T cell survival.Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccinesCerebrospinal fluid-infiltrating CD4+ T cells recognize Borrelia burgdorferi lysine-enriched protein domains and central nervous system autoantigens in early lyme encephalitisMolecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity.Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expressionMechanisms of central and peripheral T-cell tolerance: lessons from experimental models of multiple sclerosis.Molecular interactions between extracellular components of the T-cell receptor signaling complex.Mechanisms and consequences of peptide selection by the I-Ak class II molecule.Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics.Improving antigenic peptide vaccines for cancer immunotherapy using a dominant tumor-specific T cell receptor.Specificity, degeneracy, and molecular mimicry in antigen recognition by HLA-Class II restricted T cell receptors: implications for clinical medicine.CD4⁺CD25⁺Foxp3⁺ regulatory T cell formation requires more specific recognition of a self-peptide than thymocyte deletionThe lack of consensus for I-A(g7)-peptide binding motifs: is there a requirement for anchor amino acid side chains?H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejectionT cell receptor antagonism in vivo, at last.Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells.Kinetics and thermodynamics of T cell receptor- autoantigen interactions in murine experimental autoimmune encephalomyelitis.A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex.Molecular mimicry between Helicobacter pylori antigens and H+, K+ --adenosine triphosphatase in human gastric autoimmunity.Selective expansion of cross-reactive CD8(+) memory T cells by viral variants.Partially phosphorylated T cell receptor zeta molecules can inhibit T cell activation.Costimulation of T cell activation by integrin-associated protein (CD47) is an adhesion-dependent, CD28-independent signaling pathway.Functional reprogramming of the primary immune response by T cell receptor antagonism.An antagonist peptide mediates positive selection and CD4 lineage commitment of MHC class II-restricted T cells in the absence of CD4Structural and kinetic basis for heightened immunogenicity of T cell vaccines.The TCR repertoires of regulatory and conventional T cells specific for the same foreign antigen are distinct.Autoimmunity: basic mechanisms and implications in endocrine diseases. Part I.In vivo antagonism of a T cell response by an endogenously expressed ligandQuantitative theories of T-cell responsiveness.Mobilizing the low-avidity T cell repertoire to kill tumors.Recombinant T cell receptor ligands: immunomodulatory, neuroprotective and neuroregenerative effects suggest application as therapy for multiple sclerosisEffects of vaccination with altered Peptide ligand on chronic pain in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosisNovel strategies for improved cancer vaccines.Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression.Improving T cell responses to modified peptides in tumor vaccinesThe two-faced T cell epitope: examining the host-microbe interface with JanusMatrix.
P2860
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P2860
Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Structural basis for T cell re ...... e continuum of related ligands
@ast
Structural basis for T cell re ...... e continuum of related ligands
@en
type
label
Structural basis for T cell re ...... e continuum of related ligands
@ast
Structural basis for T cell re ...... e continuum of related ligands
@en
prefLabel
Structural basis for T cell re ...... e continuum of related ligands
@ast
Structural basis for T cell re ...... e continuum of related ligands
@en
P2860
P356
P1476
Structural basis for T cell re ...... e continuum of related ligands
@en
P2093
P2860
P304
P356
10.1084/JEM.184.4.1259
P407
P577
1996-10-01T00:00:00Z