Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage.
about
Interactions between double positive thymocytes and high affinity ligands presented by cortical epithelial cells generate double negative thymocytes with T cell regulatory activity.Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells.Normal immune development and glucocorticoid-induced thymocyte apoptosis in mice deficient for the T-cell death-associated gene 8 receptor.Antigen-induced T cell death is regulated by CD4 expression.Stage-dependent reactivity of thymocytes to self-peptide--MHC complexes.Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling.Development and function of T cells in T cell antigen receptor/CD3 zeta knockout mice reconstituted with Fc epsilon RI gamma.Interactions with multiple peptide ligands determine the fate of developing thymocytes.Intrathymic selection of NK1.1(+)alpha/beta T cell antigen receptor (TCR)+ cells in transgenic mice bearing TCR specific for chicken ovalbumin and restricted to I-Ad.Premature expression of T cell receptor (TCR)alphabeta suppresses TCRgammadelta gene rearrangement but permits development of gammadelta lineage T cells.Are major histocompatibility complex molecules involved in the survival of naive CD4+ T cells?CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity.Liver damage preferentially results from CD8(+) T cells triggered by high affinity peptide antigens.CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses.Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.Dendritic cells control CD4+CD25+ Treg cell suppressor function in vitro through juxtacrine delivery of IL-2.Lipid-mediated presentation of MHC class II molecules guides thymocytes to the CD4 lineage.The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor.
P2860
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P2860
Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Thymocytes can become mature T ...... + CD8+, double-positive stage.
@ast
Thymocytes can become mature T ...... + CD8+, double-positive stage.
@en
type
label
Thymocytes can become mature T ...... + CD8+, double-positive stage.
@ast
Thymocytes can become mature T ...... + CD8+, double-positive stage.
@en
prefLabel
Thymocytes can become mature T ...... + CD8+, double-positive stage.
@ast
Thymocytes can become mature T ...... + CD8+, double-positive stage.
@en
P2860
P356
P1476
Thymocytes can become mature T ...... + CD8+, double-positive stage.
@en
P2093
P2860
P304
P356
10.1084/JEM.184.5.1619
P407
P577
1996-11-01T00:00:00Z