ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
about
B-cell receptor signalling and its crosstalk with other pathways in normal and malignant cellsGrb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selectionRhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling.ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia.Differential and tumor-specific expression of CD160 in B-cell malignancies.ZAP-70: an essential kinase in T-cell signalingZAP-70 is highly expressed in most cases of childhood pre-B cell acute lymphoblastic leukemia.Immunohistochemical detection of ZAP-70 in 341 cases of non-Hodgkin and Hodgkin lymphoma.Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor.Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms.Maintenance of murine platelet homeostasis by the kinase Csk and the phosphatase CD148.
P2860
Q28245018-3F200646-D70A-4C7D-80B7-B55587AFFACEQ30156848-56BCDD61-1EFC-4A87-A130-9B13C016EAA5Q33754402-88A55EB2-2424-4CEE-B73C-5645C3A9D805Q36478480-7B34F30F-AE09-4B60-9083-DB71CCA4E8D3Q37625491-274B4355-DCA0-4D0C-BF8B-93A206344FE5Q37746517-DCA01484-8D15-44F6-A35B-46A40D7E8E82Q40003594-D0730119-6E97-4E89-A21D-25BAEFBAFED7Q40557863-DB9DFFE7-1BA8-4E59-B4CD-8499940309F1Q41463018-2C0BF760-2DDF-4460-A3D2-548C6A2E409FQ43877176-04C4BDCA-74C6-455B-9D57-77A150B38224Q45247281-7A8D4FFB-FB34-47BE-B2D3-7105E68F5222Q47231597-FA752049-108B-43B7-B613-5692CBC41D57
P2860
ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
ZAP-70 protein promotes tyrosi ...... ocytes with limiting p56(lck).
@ast
ZAP-70 protein promotes tyrosi ...... ocytes with limiting p56(lck).
@en
type
label
ZAP-70 protein promotes tyrosi ...... ocytes with limiting p56(lck).
@ast
ZAP-70 protein promotes tyrosi ...... ocytes with limiting p56(lck).
@en
prefLabel
ZAP-70 protein promotes tyrosi ...... ocytes with limiting p56(lck).
@ast
ZAP-70 protein promotes tyrosi ...... ocytes with limiting p56(lck).
@en
P2093
P2860
P356
P1476
ZAP-70 protein promotes tyrosi ...... ocytes with limiting p56(lck).
@en
P2093
P2860
P304
P356
10.1084/JEM.189.7.1163
P407
P577
1999-04-01T00:00:00Z