CSF-induced and HIV-1-mediated distinct regulation of Hck and C/EBPbeta represent a heterogeneous susceptibility of monocyte-derived macrophages to M-tropic HIV-1 infection.
about
HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenonHIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, HckHIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction.Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia.Chemical library screens targeting an HIV-1 accessory factor/host cell kinase complex identify novel antiretroviral compoundsNeutrophils activate alveolar macrophages by producing caspase-6-mediated cleavage of IL-1 receptor-associated kinase-MNef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.Effect of apoptotic cell recognition on macrophage polarization and mycobacterial persistence.Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screenAllosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor.Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBPbetaM-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia.Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic developmentInterleukin-10 induces inhibitory C/EBPbeta through STAT-3 and represses HIV-1 transcription in macrophagesCCAAT/enhancer-binding proteins and the pathogenesis of retrovirus infection.β-Catenin/TCF-4 signaling regulates susceptibility of macrophages and resistance of monocytes to HIV-1 productive infection.Catalase plays a critical role in the CSF-independent survival of human macrophages via regulation of the expression of BCL-2 family.All-Round Manipulation of the Actin Cytoskeleton by HIV.
P2860
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P2860
CSF-induced and HIV-1-mediated distinct regulation of Hck and C/EBPbeta represent a heterogeneous susceptibility of monocyte-derived macrophages to M-tropic HIV-1 infection.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
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name
CSF-induced and HIV-1-mediated ...... s to M-tropic HIV-1 infection.
@ast
CSF-induced and HIV-1-mediated ...... s to M-tropic HIV-1 infection.
@en
type
label
CSF-induced and HIV-1-mediated ...... s to M-tropic HIV-1 infection.
@ast
CSF-induced and HIV-1-mediated ...... s to M-tropic HIV-1 infection.
@en
prefLabel
CSF-induced and HIV-1-mediated ...... s to M-tropic HIV-1 infection.
@ast
CSF-induced and HIV-1-mediated ...... s to M-tropic HIV-1 infection.
@en
P2093
P2860
P356
P1476
CSF-induced and HIV-1-mediated ...... s to M-tropic HIV-1 infection.
@en
P2093
Aikichi Iwamoto
Iwao Komuro
Kiyoko S Kagawa
Sachiko Yasuda
Yasuko Yokota
P2860
P304
P356
10.1084/JEM.20022018
P407
P577
2003-08-01T00:00:00Z