Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis.
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Science review: role of coagulation protease cascades in sepsisCrystal Structure of Thrombin Bound to the Uncleaved Extracellular Fragment of PAR1Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosisBidirectional regulation of renal hemodynamics by activation of PAR1 and PAR2 in isolated perfused rat kidneySynthesis of Anticoagulantly Active Heparan Sulfate Proteoglycans by Glomerular Epithelial Cells Involves Multiple 3-O-Sulfotransferase Isoforms and a Limiting Precursor PoolTissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice.Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice.Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia.Role of G protein-coupled receptors in inflammation.Functional role of kallikrein 6 in regulating immune cell survival.Synergistic induction of tissue factor by coagulation factor Xa and TNF: evidence for involvement of negative regulatory signaling cascadesPlasminogen activator inhibitor-1 and the kidney.Phenotypic analysis of mice lacking the Tmprss2-encoded proteasePR3 and elastase alter PAR1 signaling and trigger vWF release via a calcium-independent mechanism from glomerular endothelial cells.Haemostatic system in inflammatory bowel diseases: new players in gut inflammation.Urinary thrombin: a novel marker of glomerular inflammation for the diagnosis of crescentic glomerulonephritis (prospective observational study)Protease-activated receptors in the cardiovascular system.Expression of protease-activated receptor-1, -2, -3, and -4 in control and experimentally inflamed mouse bladder.Inhibition of the tissue factor-thrombin pathway limits infarct size after myocardial ischemia-reperfusion injury by reducing inflammation.Protease-activated receptor-2 augments experimental crescentic glomerulonephritisAmelioration of collagen-induced arthritis by thrombin inhibition.CovRS-Regulated Transcriptome Analysis of a Hypervirulent M23 Strain of Group A Streptococcus pyogenes Provides New Insights into Virulence Determinants.Tissue factor: a mediator of inflammatory cell recruitment, tissue injury, and thrombus formation in experimental colitis.Stanniocalcin-1 inhibits thrombin-induced signaling and protects from bleomycin-induced lung injury.Activated protein C-cleaved protease activated receptor-1 is retained on the endothelial cell surface even in the presence of thrombinPAR1 contributes to influenza A virus pathogenicity in miceThe interface between coagulation and immunity.Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.Over-expression of the thrombin receptor (PAR-1) in the placenta in preeclampsia: a mechanism for the intersection of coagulation and inflammation.The emerging role of coagulation proteases in kidney disease.Concentration dependent dual effect of thrombin in endothelial cells via Par-1 and Pi3 Kinase.Protease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice.Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury.Proteinase activated receptor 1 mediated fibrosis in a mouse model of liver injury: a role for bone marrow derived macrophages.Novel aspects of fibrin(ogen) fragments during inflammation.The roles of thrombin and protease-activated receptors in inflammation.Update on crescentic glomerulonephritis.Protease-activated receptor 4: a critical participator in inflammatory response.The characteristics of thrombin in osteoarthritic pathogenesis and treatment.Dabigatran vs. warfarin in relation to the presence of left ventricular hypertrophy in patients with atrial fibrillation- the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) study.
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P2860
Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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@zh-hant
name
Protease-activated receptor 1 ...... crescentic glomerulonephritis.
@ast
Protease-activated receptor 1 ...... crescentic glomerulonephritis.
@en
type
label
Protease-activated receptor 1 ...... crescentic glomerulonephritis.
@ast
Protease-activated receptor 1 ...... crescentic glomerulonephritis.
@en
prefLabel
Protease-activated receptor 1 ...... crescentic glomerulonephritis.
@ast
Protease-activated receptor 1 ...... crescentic glomerulonephritis.
@en
P2093
P2860
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P1476
Protease-activated receptor 1 ...... crescentic glomerulonephritis.
@en
P2093
M A Cunningham
P G Tipping
S R Coughlin
S R Holdsworth
P2860
P304
P356
10.1084/JEM.191.3.455
P407
P577
2000-02-01T00:00:00Z