T cell receptor (TCR) mini-gene mRNA expression regulated by nonsense codons: a nuclear-associated translation-like mechanism
about
A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4EPre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctionsA nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decayRespiratory syncytial virus infection alters surfactant protein A expression in human pulmonary epithelial cells by reducing translation efficiencyThe nonsense-mediated decay pathway and mutually exclusive expression of alternatively spliced FGFR2IIIb and -IIIc mRNAsRegulation of the processing of glucose-6-phosphate dehydrogenase mRNA by nutritional status.Frame-disrupting mutations elicit pre-mRNA accumulation independently of frame disruptionBoundary-independent polar nonsense-mediated decay.Intranuclear degradation of nonsense codon-containing mRNAAt least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation.T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts.Unspliced precursors of NMD-sensitive β-globin transcripts exhibit decreased steady-state levels in erythroid cellsMultifunctional regulatory proteins that control gene expression in both the nucleus and the cytoplasm.Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm.Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3' end processing of the corresponding pre-mRNA.Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements.A quantitative analysis of intron effects on mammalian gene expression.Premature termination codons do not affect the rate of splicing of neighboring introns.Nonsense-associated alternative splicing of T-cell receptor beta genes: no evidence for frame dependence5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.Inhibition of the ubiquitin-proteasome system induces stress granule formation.Unexpected roles for UPF1 in HIV-1 RNA metabolism and translation.AUG sequences are required to sustain nonsense-codon-mediated suppression of splicingPerturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice.A Hox gene mutation that triggers nonsense-mediated RNA decay and affects alternative splicing during Drosophila development.An alternative branch of the nonsense-mediated decay pathwayA mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells.Premature termination codons in PRPF31 cause retinitis pigmentosa via haploinsufficiency due to nonsense-mediated mRNA decay.Preferential expression of hPGFS in primary SCCHN and tumour cell lines derived from respiratory and digestive organs.Regulation of nonsense-mediated mRNA decay: implications for physiology and disease.Regulation of nonsense-mediated mRNA decay.Infrequent translation of a nonsense codon is sufficient to decrease mRNA levelStress and the nonsense-mediated RNA decay pathway.Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position.Stop codon-mediated suppression of splicing is a novel nuclear scanning mechanism not affected by elements of protein synthesis and NMD.Unspliced Rous sarcoma virus genomic RNAs are translated and subjected to nonsense-mediated mRNA decay before packaging.Nonsense codons trigger an RNA partitioning shift.Binary specification of nonsense codons by splicing and cytoplasmic translationIntramuscular electroporation delivery of IFN-alpha gene therapy for inhibition of tumor growth located at a distant site.Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame.
P2860
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P2860
T cell receptor (TCR) mini-gene mRNA expression regulated by nonsense codons: a nuclear-associated translation-like mechanism
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
T cell receptor (TCR) mini-gen ...... ted translation-like mechanism
@ast
T cell receptor (TCR) mini-gen ...... ted translation-like mechanism
@en
type
label
T cell receptor (TCR) mini-gen ...... ted translation-like mechanism
@ast
T cell receptor (TCR) mini-gen ...... ted translation-like mechanism
@en
prefLabel
T cell receptor (TCR) mini-gen ...... ted translation-like mechanism
@ast
T cell receptor (TCR) mini-gen ...... ted translation-like mechanism
@en
P2093
P2860
P356
P1476
T cell receptor (TCR) mini-gen ...... ted translation-like mechanism
@en
P2093
P2860
P304
P356
10.1084/JEM.185.6.985
P407
P577
1997-03-01T00:00:00Z