Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication. - Wikidata - awgldk - TriplyDB

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

http://www.wikidata.org/entity/Q36381109

about

The cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replication Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase.Regulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidization A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapy Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle Identification and initial characterization of three novel cyclin-related proteins of the human malaria parasite Plasmodium falciparum Molecular basis for viral selective replication in cancer cells: activation of CDK2 by adenovirus-induced cyclin E Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro Chromatin decondensation in S-phase involves recruitment of Cdk2 by Cdc45 and histone H1 phosphorylation A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.Wee1 kinase alters cyclin E/Cdk2 and promotes apoptosis during the early embryonic development of Xenopus laevis Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation.Xenopus Cdc6 performs separate functions in initiating DNA replication Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch.Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast.cAMP-mediated inhibition of DNA replication and S phase progression: involvement of Rb, p21Cip1, and PCNA.Analysis of Cdc6 function in the assembly of mammalian prereplication complexes Drosophila cyclin E interacts with components of the Brahma complex The origin of CDK regulation Phosphorylation of Xenopus Rad1 and Hus1 defines a readout for ATR activation that is independent of Claspin and the Rad9 carboxy terminus Replication licensing promotes cyclin D1 expression and G1 progression in untransformed human cells.SNR1 (INI1/SNF5) mediates important cell growth functions of the Drosophila Brahma (SWI/SNF) chromatin remodeling complex.Phospho-regulation of HsCdc14A By Polo-like kinase 1 is essential for mitotic progression.Origin licensing and programmed cell death: a hypothesis.Virotherapy targeting cyclin E overexpression in tumors with adenovirus-enhanced cancer-selective promoter.Oncolytic adenovirus targeting cyclin E overexpression repressed tumor growth in syngeneic immunocompetent mice.Interwoven ubiquitination oscillators and control of cell cycle transitions.Drosophila follicle cell amplicons as models for metazoan DNA replication: a cyclinE mutant exhibits increased replication fork elongation Cell cycle in mouse development.Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation.ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6.Molecular evolution of Drosophila Cdc6, an essential DNA replication-licensing gene, suggests an adaptive choice of replication origins.Mammalian interphase cdks: dispensable master regulators of the cell cycle.A jekyll and hyde role of cyclin E in the genotoxic stress response: switching from cell cycle control to apoptosis regulation.SUMO2/3 modification of cyclin E contributes to the control of replication origin firing.Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription.

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Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

http://www.wikidata.org/entity/Q36381109

description

2001 nî lūn-bûn

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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2001年學術文章

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2001年學術文章

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name

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

@ast

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

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type

label

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

@ast

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

@en

prefLabel

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

@ast

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

@en

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P1476

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication.

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P2093

B K Kaiser

http://www.w3.org/2001/XMLSchema#string

C Swanson

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L Furstenthal

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P K Jackson

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P2860

Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

A human protein related to yeast Cdc6p

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes

Cyclin-binding motifs are essential for the function of p21CIP1

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators

Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry

Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

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6

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