A requirement for replication in activation of the ATR-dependent DNA damage checkpoint. - Wikidata - awgldk - TriplyDB

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

http://www.wikidata.org/entity/Q30848079

about

Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases The Fanconi anemia protein FANCM is controlled by FANCD2 and the ATR/ATM pathways Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activation The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication.Hbo1 Links p53-dependent stress signaling to DNA replication licensing.A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts.Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin.A novel protein activity mediates DNA binding of an ATR-ATRIP complex.Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling.The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1.Global regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.Kinetics of the UV-induced DNA damage response in relation to cell cycle phase. Correlation with DNA replication.Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.Continued primer synthesis at stalled replication forks contributes to checkpoint activation.Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts.Changes in regulatory phosphorylation of Cdc25C Ser287 and Wee1 Ser549 during normal cell cycle progression and checkpoint arrests.Brc1-dependent recovery from replication stress.Replication-mediated disassociation of replication protein A-XPA complex upon DNA damage: implications for RPA handing off.Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks Phosphorylation of Xenopus Rad1 and Hus1 defines a readout for ATR activation that is independent of Claspin and the Rad9 carboxy terminus The structural determinants of checkpoint activation Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structures RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage.UV irradiation induces a postreplication DNA damage checkpoint.TIF1 activates the intra-S-phase checkpoint response in the diploid micronucleus and amitotic polyploid macronucleus of Tetrahymena.The fork and the kinase: a DNA replication tale from a CHK1 perspective.XRad17 is required for the activation of XChk1 but not XCds1 during checkpoint signaling in Xenopus.Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression Checkpoint silencing during the DNA damage response in Caenorhabditis elegans embryos The conserved C terminus of Claspin interacts with Rad9 and promotes rapid activation of Chk1.

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P2860

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

http://www.wikidata.org/entity/Q30848079

description

2002 nî lūn-bûn

@nan

2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

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2002年論文

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2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

@ast

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

@en

type

label

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

@ast

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

@en

prefLabel

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

@ast

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

@en

P1433

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P1433

Genes & Development

P1476

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint.

@en

P2093

Karlene A Cimprich

http://www.w3.org/2001/XMLSchema#string

Mohammad Hekmat-Nejad

http://www.w3.org/2001/XMLSchema#string

Muh-Ching Yee

http://www.w3.org/2001/XMLSchema#string

Patrick J Lupardus

http://www.w3.org/2001/XMLSchema#string

Tony Byun

http://www.w3.org/2001/XMLSchema#string

P2860

Geminin, an inhibitor of DNA replication, is degraded during mitosis

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

The DNA damage response: putting checkpoints in perspective

Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha

ATR and ATRIP: partners in checkpoint signaling

Claspin, a Novel Protein Required for the Activation of Chk1 during a DNA Replication Checkpoint Response in Xenopus Egg Extracts

Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint

Cell cycle checkpoint signaling through the ATM and ATR kinases

DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint

A unified view of the DNA-damage checkpoint.

P304

2327-2332

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scholarly article

P356

10.1101/GAD.1013502

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P433

18

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16

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2002-09-01T00:00:00Z

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11157974

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12231621

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187437

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