Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells.
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PIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesisUnconventional secretion of synuclein-γ promotes tumor cell invasionCharacterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complexDirect binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I traffickingCloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinaseDeficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndromeBeclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi networkA role for sorting nexin 2 in epidermal growth factor receptor down-regulation: evidence for distinct functions of sorting nexin 1 and 2 in protein traffickingMannose 6-phosphate receptors regulate the formation of clathrin-coated vesicles in the TGNStructure and Function of Vps15 in the Endosomal G Protein Signaling Pathway ,Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasisTwo distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiaeAssortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae.A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinasePhosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localizationMammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyveSyntaxin 12, a member of the syntaxin family localized to the endosomeCharacterization of the association of the actin-binding protein, IQGAP, and activated Cdc42 with Golgi membranesLigands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activityOverexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturationWortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reactionMechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis.Vp165 and GLUT4 share similar vesicle pools along their trafficking pathways in rat adipose cellsComplementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinasesThe secretory pathway of protists: spatial and functional organization and evolutionBeclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAGA role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophagesThe HIV-1 Nef protein as a target for antiretroviral therapy.Resting (basal) secretion of proteins is provided by the minor regulated and constitutive-like pathways and not granule exocytosis in parotid acinar cells.Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cellsApoptosis by Cd2+ or CdMT in proximal tubule cells: different uptake routes and permissive role of endo/lysosomal CdMT uptake.Role of class III phosphatidylinositol 3-kinase during programmed nuclear death of Tetrahymena thermophila.Regulation of endosome fusion.Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site.PTEN 2, a Golgi-associated testis-specific homologue of the PTEN tumor suppressor lipid phosphatase.SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition.Membrane transport in Caenorhabditis elegans: an essential role for VPS34 at the nuclear membrane.The palmitoyltransferase of the cation-dependent mannose 6-phosphate receptor cycles between the plasma membrane and endosomesLipid metabolism and vesicle trafficking: more than just greasing the transport machinery.
P2860
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P2860
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Role for phosphatidylinositol ...... al enzymes in mammalian cells.
@ast
Role for phosphatidylinositol ...... al enzymes in mammalian cells.
@en
type
label
Role for phosphatidylinositol ...... al enzymes in mammalian cells.
@ast
Role for phosphatidylinositol ...... al enzymes in mammalian cells.
@en
prefLabel
Role for phosphatidylinositol ...... al enzymes in mammalian cells.
@ast
Role for phosphatidylinositol ...... al enzymes in mammalian cells.
@en
P2093
P2860
P356
P1476
Role for phosphatidylinositol ...... al enzymes in mammalian cells.
@en
P2093
P2860
P304
P356
10.1083/JCB.130.4.781
P407
P577
1995-08-01T00:00:00Z