Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.
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Bacterial flagella: twist and stick, or dodge across the kingdomsPolicing the cytosol--bacterial-sensing inflammasome receptors and pathwaysCrystal structure of NLRC4 reveals its autoinhibition mechanismHolding the inflammatory system in check: NLRs keep it coolInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseInteractions of Salmonella with animals and plantsStructural mechanisms of inflammasome assemblyThe nucleic acid-sensing inflammasomesA novel conserved mechanism for plant NLR protein pairs: the "integrated decoy" hypothesisStructural mechanisms in NLR inflammasome signaling.Surfactant protein A binds flagellin enhancing phagocytosis and IL-1β production.Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.Signal transduction by a fungal NOD-like receptor based on propagation of a prion amyloid foldStructural biology of innate immunity.Emerging significance of NLRs in inflammatory bowel disease.Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf.Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on FlagellinMechanisms and pathways of innate immune activation and regulation in health and cancer.Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.Constitutive Activation of the Nlrc4 Inflammasome Prevents Hepatic Fibrosis and Promotes Hepatic Regeneration after Partial Hepatectomy.Protein-protein interactions in the RPS4/RRS1 immune receptor complex.Carboxyl-terminal fusion of E7 into Flagellin shifts TLR5 activation to NLRC4/NAIP5 activation and induces TLR5-independent anti-tumor immunity.Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation.Unsolved Mysteries in NLR Biology.Post-translational regulation of inflammasomes.Flagellin induces antibody responses through a TLR5- and inflammasome-independent pathwayThe Goldilocks Conundrum: NLR Inflammasome Modulation of Gastrointestinal Inflammation during Inflammatory Bowel DiseaseApoptosome structure, assembly, and procaspase activation.Regulation where autophagy intersects the inflammasome.Mechanisms of NOD-like receptor-associated inflammasome activation.Interactions between Nod-Like Receptors and Intestinal Bacteria.Licensing Adaptive Immunity by NOD-Like Receptors.Emerging Concepts about NAIP/NLRC4 Inflammasomes.The NAIP-NLRC4 inflammasome in innate immune detection of bacterial flagellin and type III secretion apparatus.The hierarchical structural architecture of inflammasomes, supramolecular inflammatory machines.Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes.Designing disorder: Tales of the unexpected tails.Vaccine technologies: From whole organisms to rationally designed protein assemblies.Pathogen perception by NLRs in plants and animals: Parallel worlds.Structural Mechanisms in NLR Inflammasome Assembly and Signaling.
P2860
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P2860
Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Formation and structure of a N ...... terminal regions of flagellin.
@ast
Formation and structure of a N ...... terminal regions of flagellin.
@en
type
label
Formation and structure of a N ...... terminal regions of flagellin.
@ast
Formation and structure of a N ...... terminal regions of flagellin.
@en
prefLabel
Formation and structure of a N ...... terminal regions of flagellin.
@ast
Formation and structure of a N ...... terminal regions of flagellin.
@en
P2093
P2860
P356
P1476
Formation and structure of a N ...... -terminal regions of flagellin
@en
P2093
Arie Schouten
Eric G Huizinga
Marian Versteeg
T Harma C Brondijk
P2860
P304
38460-38472
P356
10.1074/JBC.M112.393512
P407
P577
2012-09-25T00:00:00Z