Constitutive cell surface association between CD4 and CCR5. - Wikidata - awgldk - TriplyDB

Constitutive cell surface association between CD4 and CCR5.

Constitutive cell surface association between CD4 and CCR5.

http://www.wikidata.org/entity/Q36397946

about

Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells Virus entry, assembly, budding, and membrane rafts Pit2 assemblies at the cell surface are modulated by extracellular inorganic phosphate concentration The influence of CD4 and CXCR4 on maedi-visna virus-induced syncytium formation Variable sensitivity of CCR5-tropic human immunodeficiency virus type 1 isolates to inhibition by RANTES analogs Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140 Proteomic-based identification of CD4-interacting proteins in human primary macrophages Two strikingly different signaling pathways are induced by meningococcal type IV pili on endothelial and epithelial cells Physiological levels of virion-associated human immunodeficiency virus type 1 envelope induce coreceptor-dependent calcium flux.Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes.Role of cholesterol in human immunodeficiency virus type 1 envelope protein-mediated fusion with host cells New cholesterol-specific antibodies remodel HIV-1 target cells' surface and inhibit their in vitro virus production.CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surface Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120.N-linked glycosylation of CXCR4 masks coreceptor function for CCR5-dependent human immunodeficiency virus type 1 isolates.Glycosphingolipids promote entry of a broad range of human immunodeficiency virus type 1 isolates into cell lines expressing CD4, CXCR4, and/or CCR5.Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1 Chemokine receptor oligomerization and allostery.Mutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolates CD4-independent use of Rhesus CCR5 by human immunodeficiency virus Type 2 implicates an electrostatic interaction between the CCR5 N terminus and the gp120 C4 domain.Viral exploitation and subversion of the immune system through chemokine mimicry.Segregation of CD4 and CXCR4 into distinct lipid microdomains in T lymphocytes suggests a mechanism for membrane destabilization by human immunodeficiency virus Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles.Sphingomyelin synthase 2, but not sphingomyelin synthase 1, is involved in HIV-1 envelope-mediated membrane fusion.LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection.Localization of CD4 and CCR5 in living cells.Chemokine receptors: emerging opportunities for new anti-HIV therapies.The tyrosine kinase inhibitor genistein blocks HIV-1 infection in primary human macrophages.Cooperative subunit interactions within the oligomeric envelope glycoprotein of HIV-1: functional complementation of specific defects in gp120 and gp41.CCR5 antagonist TD-0680 uses a novel mechanism for enhanced potency against HIV-1 entry, cell-mediated infection, and a resistant variant.The trinity of the cortical actin in the initiation of HIV-1 infection New insights into viral structure and virus-cell interactions through proteomics.Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.Functional and genetic analysis of coreceptor usage by dualtropic HIV-1 subtype C isolates.Increased efficacy of HIV-1 neutralization by antibodies at low CCR5 surface concentration.Rational design of novel HIV-1 entry inhibitors by RANTES engineering Complementation of diverse HIV-1 Env defects through cooperative subunit interactions: a general property of the functional trimer.Design and evaluation of multi-gene, multi-clade HIV-1 MVA vaccines.CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface Palmitoylation of CCR5 is critical for receptor trafficking and efficient activation of intracellular signaling pathways.

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P2860

Constitutive cell surface association between CD4 and CCR5.

http://www.wikidata.org/entity/Q36397946

description

1999 nî lūn-bûn

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1999年の論文

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1999年学术文章

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1999年学术文章

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1999年学术文章

@zh-hans

1999年学术文章

@zh-my

1999年学术文章

@zh-sg

1999年學術文章

@yue

1999年學術文章

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1999年學術文章

@zh-hant

name

Constitutive cell surface association between CD4 and CCR5.

@ast

Constitutive cell surface association between CD4 and CCR5.

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type

label

Constitutive cell surface association between CD4 and CCR5.

@ast

Constitutive cell surface association between CD4 and CCR5.

@en

prefLabel

Constitutive cell surface association between CD4 and CCR5.

@ast

Constitutive cell surface association between CD4 and CCR5.

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PNAS.96.13.7496

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Constitutive cell surface association between CD4 and CCR5

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P2093

C C Broder

http://www.w3.org/2001/XMLSchema#string

D S Dimitrov

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H Chen

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L Wu

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Q J Sattentau

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T S Stantchev

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X Xiao

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Y R Feng

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Z Shen

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P2860

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

Identification of a major co-receptor for primary isolates of HIV-1

Dimeric association and segmental variability in the structure of human CD4

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

HIV and the 7-transmembrane domain receptors

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

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7496-7501

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