Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
about
Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st centuryThe Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer's Disease and Spinal Cord InjuryA Role for the Brain RAS in Alzheimer's and Parkinson's DiseasesExperimental and computational analysis of polyglutamine-mediated cytotoxicityHeat shock proteins in neurodegenerative disorders and agingPathogenesis of Alzheimer's diseaseMethionine sulfoxides on prion protein Helix-3 switch on the alpha-fold destabilization required for conversion.Activation of proteasome by insulin-like growth factor-I may enhance clearance of oxidized proteins in the brain.Proteasome inhibition modulates kinase activation in neural cells: relevance to ubiquitination, ribosomes, and survival.Intersection between metabolic dysfunction, high fat diet consumption, and brain aging.Cellular stress response pathways and ageing: intricate molecular relationshipsGene expression in the hippocampus: regionally specific effects of aging and caloric restrictionCorneal wound healing is compromised by immunoproteasome deficiency.Neocortex and allocortex respond differentially to cellular stress in vitro and aging in vivoPoly-Ub-substrate-degradative activity of 26S proteasome is not impaired in the aging rat brain.A genome-wide longitudinal transcriptome analysis of the aging model Podospora anserina.Increased protein hydrophobicity in response to aging and Alzheimer diseaseImmunoproteasome deficiency protects in the retina after optic nerve crush.Lifespan of mice and primates correlates with immunoproteasome expressionAging is associated with hypoxia and oxidative stress in adipose tissue: implications for adipose function.Oxidative stress in aging human skin.Dipeptidyl peptidase 4 inhibition may facilitate healing of chronic foot ulcers in patients with type 2 diabetes.Ubiquitin proteasome system as a pharmacological target in neurodegeneration.Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 subunit upon mitochondrial dysfunction in neurons.Aging and dietary restriction effects on ubiquitination, sumoylation, and the proteasome in the heart.Oxidative stress adaptation with acute, chronic, and repeated stress.Effects of aging and dietary restriction on ubiquitination, sumoylation, and the proteasome in the spleenLipofuscin: formation, effects and role of macroautophagyDifferential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons.Imaging of radiation effects on cellular 26S proteasome function in situ.Proteasome modulates mitochondrial function during cellular senescence.Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle.Hypoxia inducible factor 1 as a therapeutic target in ischemic stroke.Proteasome inhibitor MG-132 induces C6 glioma cell apoptosis via oxidative stress.Proteasomal dysfunction in aging and Huntington disease.Hypoxia inducible factor-1: its potential role in cerebral ischemia.HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress.Selective vulnerability of neurons to acute toxicity after proteasome inhibitor treatment: implications for oxidative stress and insolubility of newly synthesized proteins.Differential roles of proteasome and immunoproteasome regulators Pa28αβ, Pa28γ and Pa200 in the degradation of oxidized proteins.Tau protein degradation is catalyzed by the ATP/ubiquitin-independent 20S proteasome under normal cell conditions.
P2860
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P2860
Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
@ast
Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
@en
type
label
Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
@ast
Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
@en
prefLabel
Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
@ast
Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
@en
P2093
P356
P1476
Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
@en
P2093
Edgardo Dimayuga
Jeffrey N Keller
Qunxing Ding
P304
P356
10.1089/ARS.2006.8.163
P577
2006-01-01T00:00:00Z