Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle.
about
The role of oxidative stress in Parkinson's diseaseAutophagy, mitochondria and oxidative stress: cross-talk and redox signallingThe Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative DiseasesRelationship between Oxidative Stress, Circadian Rhythms, and AMDProtein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degenerationRedox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain.Proteomic characterization of an isolated fraction of synthetic proteasome inhibitor (PSI)-induced inclusions in PC12 cells might offer clues to aggresomes as a cellular defensive response against proteasome inhibition by PSI.PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.Inhibition of glycolysis attenuates 4-hydroxynonenal-dependent autophagy and exacerbates apoptosis in differentiated SH-SY5Y neuroblastoma cellsThe neurogenic basic helix-loop-helix transcription factor NeuroD6 confers tolerance to oxidative stress by triggering an antioxidant response and sustaining the mitochondrial biomass.Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1Transcranial near-infrared laser therapy applied to promote clinical recovery in acute and chronic neurodegenerative diseases.Astrocytes and therapeutics for Parkinson's disease.Protein kinase D1 (PKD1) phosphorylation promotes dopaminergic neuronal survival during 6-OHDA-induced oxidative stress.Novel variant Pro143Ala in HTRA2 contributes to Parkinson's disease by inducing hyperphosphorylation of HTRA2 protein in mitochondria.Supramolecular non-amyloid intermediates in the early stages of α-synuclein aggregation.Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment.Parkinson's disease and autophagy.Drug discovery in Parkinson's disease-Update and developments in the use of cellular models.Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stressUpstream Pathways Controlling Mitochondrial Function in Major Psychosis: A Focus on Bipolar DisorderInhibition of the Fe(III)-catalyzed dopamine oxidation by ATP and its relevance to oxidative stress in Parkinson's diseaseExplaining ADAGIO: a critical review of the biological basis for the clinical effects of rasagiline.Defective autophagy in Parkinson's disease: role of oxidative stress.Recent advances in α-synuclein functions, advanced glycation, and toxicity: implications for Parkinson's disease.Coenzyme Q10 depletion in medical and neuropsychiatric disorders: potential repercussions and therapeutic implications.Defective autophagy in Parkinson's disease: lessons from genetics.Sirtuins and proteolytic systems: implications for pathogenesis of synucleinopathies.Regulation of autophagy, mitochondrial dynamics and cellular bioenergetics by 4-hydroxynonenal in primary neurons.GPR30 Activation Contributes to the Puerarin-Mediated Neuroprotection in MPP+-Induced SH-SY5Y Cell Death.Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson's disease.Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress.Neuroprotective effects of ganoderma lucidum polysaccharides against oxidative stress-induced neuronal apoptosis.Real-Time Amperometric Recording of Extracellular H₂O₂ in the Brain of Immunocompromised Mice: An In Vitro, Ex Vivo and In Vivo Characterisation Study.Imaging nanometer-sized α-synuclein aggregates by superresolution fluorescence localization microscopy.Neurodegenerative Shielding by Curcumin and Its Derivatives on Brain Lesions Induced by 6-OHDA Model of Parkinson's Disease in Albino Wistar Rats.Akt as a victim, villain and potential hero in Parkinson's disease pathophysiology and treatment.Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity.Memory impairment and hippocampus specific protein oxidation induced by ethanol intake and 3, 4-methylenedioxymethamphetamine (MDMA) in mice.Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy.
P2860
Q24307946-9568D68D-D5B4-409D-8EE6-F0B1FC308D12Q24608960-80D5A835-4E91-46C3-966D-9067D9FF61E6Q26750137-7D2E3A8F-70A1-42D5-A4F9-FF3D92FF356FQ26765278-F24353B6-977C-436F-982C-783DA39F57FFQ28582417-77FC8EE4-2595-46F6-89B6-64B0BF21FE86Q30367032-78DE367B-7FA5-4380-942D-2C867CB2F50FQ30479870-82E1B5C0-9A36-4B18-95C0-D817994C9069Q30583566-01908E83-CB71-4B92-A4E9-54CCA4969848Q33638710-078739F7-4489-4205-A033-BC71D8867A65Q33870484-9233B93E-F805-4FB2-860D-0FBEDE31C0F9Q34079628-73BBDF0D-3C41-41F2-B904-6EA3457493BEQ34092740-807EA8F8-F3CA-499F-8B34-6704B760C32CQ34168266-82390A3E-73F3-43DC-8C53-88EF38A786EFQ35164624-8E53B4A9-9B0B-4BA9-A659-A7F9031A0B62Q35544534-3120A4AE-40D8-4E93-A5AA-407CC6BDF501Q35810050-396BA00E-BB56-4E6A-9AE8-9359EEA18AE2Q35853020-71CDC5E3-2E36-410B-8508-6F9A1C2F4B5CQ36355428-2931FEC1-3BA6-400C-8A94-8DFC234F661DQ36680414-B04B2944-A82A-4317-A19F-51ED414027C8Q36767908-BC4AC54A-BCB2-4B73-BA6F-5DBF82ED1451Q37123412-99CF5EA5-50A4-494A-BE9F-D74DB7823ADBQ37186193-F0D94DE7-B2A4-4D77-8669-7EC3BF0BE06CQ37939755-C004EC7F-7842-4275-B3F3-C81679E69A52Q38035191-67A4AA18-CD99-4BF6-BAA3-670C9E0AF715Q38038126-2E56B0A4-DED2-4029-837C-AA857AABB674Q38114007-7EA6CAF8-19E6-489D-9FB8-30410DDDA9CEQ38225786-70C1D8F7-475C-413D-94DB-C8B23F12777BQ38462113-609F0427-6E1D-4BA7-867E-4116713A202FQ38610212-FB71D990-2C25-4788-9626-8C5D3FFD9A8DQ38735026-FBEBAC3C-B857-43CD-A72D-AE1466BB840EQ38816615-04A1FE33-D74E-468D-B944-033F48133250Q38951473-E37C2540-6D8D-4EE7-9B13-101E6C1EDA5DQ41043789-CB4A7343-5562-41EE-9835-CBEAA98160A6Q41205578-526A3C1C-A6A0-4810-8680-E859DFCFBEDCQ41613707-AA7B1DF4-4307-44DC-9BCC-A1A7C4B77B46Q41853483-A0E4B256-DDBF-4699-9BC2-150C3A39D6F0Q42148662-68079637-7046-459A-B80B-2F6E301E6F27Q43193570-751F3C6D-3841-4E0F-9B3E-4A37A2AD7457Q43776203-F589A148-0EAD-4701-8120-5F84517B89D0Q47833346-3AD3D9DA-33FD-4F9B-B127-84105EB553BD
P2860
Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 June 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Oxidative modifications, mitoc ...... lost in the Bermuda triangle.
@en
Oxidative modifications, mitoc ...... lost in the Bermuda triangle.
@nl
type
label
Oxidative modifications, mitoc ...... lost in the Bermuda triangle.
@en
Oxidative modifications, mitoc ...... lost in the Bermuda triangle.
@nl
prefLabel
Oxidative modifications, mitoc ...... lost in the Bermuda triangle.
@en
Oxidative modifications, mitoc ...... lost in the Bermuda triangle.
@nl
P2860
P356
P1476
Oxidative modifications, mitoc ...... lost in the Bermuda triangle.
@en
P2093
Harry Ischiropoulos
Kristen A Malkus
P2860
P2888
P356
10.1186/1750-1326-4-24
P50
P577
2009-06-05T00:00:00Z
P5875
P6179
1001206933