Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production.
about
The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cellsDirect inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding proteinMast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxisBruton's tyrosine kinase (Btk) associates with protein kinase C muBiochemical interactions integrating Itk with the T cell receptor-initiated signaling cascadePKCbeta modulates antigen receptor signaling via regulation of Btk membrane localizationSilencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA)RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cellsThe Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulationIdentification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse BtkPrimate TNF promoters reveal markers of phylogeny and evolution of innate immunityIn situ detection of activated Bruton's tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies.Small interfering RNA screen for phosphatases involved in IgE-mediated mast cell degranulation.Stimulus-specific assembly of enhancer complexes on the tumor necrosis factor alpha gene promoter.SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.T-cell-dependent control of acute Giardia lamblia infections in mice.Btk-dependent Rac activation and actin rearrangement following FcepsilonRI aggregation promotes enhanced chemotactic responses of mast cellsBTK inhibitors in chronic lymphocytic leukemia: a glimpse to the future.B cells delay neutrophil migration toward the site of stimulus: tardiness critical for effective bacillus Calmette-Guérin vaccination against tuberculosis infection in mice.Functional analysis of Lyn kinase A and B isoforms reveals redundant and distinct roles in Fc epsilon RI-dependent mast cell activation.Tyrosine Kinase Inhibitors and Therapeutic Antibodies in Advanced Eosinophilic Disorders and Systemic Mastocytosis.Absence of Tec family kinases interleukin-2 inducible T cell kinase (Itk) and Bruton's tyrosine kinase (Btk) severely impairs Fc epsilonRI-dependent mast cell responses.Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cellsThe transcription factor MAZR preferentially acts as a transcriptional repressor in mast cells and plays a minor role in the regulation of effector functions in response to FcεRI stimulation.The role of Tec family kinases in T cell development and function.Regulation of protein kinase CbetaI by two protein-tyrosine kinases, Btk and SykA novel role for Bruton's tyrosine kinase in hepatocyte growth factor-mediated immunoregulation of dendritic cells.Inhibitory effect of methyleugenol on IgE-mediated allergic inflammation in RBL-2H3 cellsModeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma.A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expressionRegulation of mast cell survival and function by tuberous sclerosis complex 1.The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinibThe Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase LynThe transcription factor Zeb2 regulates signaling in mast cellsThe transcription factor NFATp plays a key role in susceptibility to TB in mice.Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells.Signal transduction and chemotaxis in mast cellsFc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane.Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activationAkt-dependent cytokine production in mast cells.
P2860
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P2860
Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Involvement of Bruton's tyrosi ...... ation and cytokine production.
@ast
Involvement of Bruton's tyrosi ...... ation and cytokine production.
@en
type
label
Involvement of Bruton's tyrosi ...... ation and cytokine production.
@ast
Involvement of Bruton's tyrosi ...... ation and cytokine production.
@en
prefLabel
Involvement of Bruton's tyrosi ...... ation and cytokine production.
@ast
Involvement of Bruton's tyrosi ...... ation and cytokine production.
@en
P2093
P2860
P356
P1476
Involvement of Bruton's tyrosi ...... ation and cytokine production.
@en
P2093
A E Goldfeld
M Maeda-Yamamoto
S E Hartman
P2860
P304
P356
10.1084/JEM.187.8.1235
P407
P577
1998-04-01T00:00:00Z