Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
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Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/TxkBruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding proteinEtk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinasesTAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptorBAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagementEtk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cellsSignal-dependent membrane targeting by pleckstrin homology (PH) domainsStructure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemiaIdentification of the binding site for Gqalpha on its effector Bruton's tyrosine kinaseTruncation of C-mip (Tc-mip), a new proximal signaling protein, induces c-maf Th2 transcription factor and cytoskeleton reorganizationNeuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinaseCrystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemiaStructures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinasesX-ray crystal structure of bone marrow kinase in the x chromosome: a Tec family kinaseTyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factorsInteraction of SLP adaptors with the SH2 domain of Tec family kinasesProtein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinasesBiochemical interactions integrating Itk with the T cell receptor-initiated signaling cascadeMechanism of Bruton's tyrosine kinase-mediated recruitment and regulation of TFII-IIdentification of phosphorylation sites for Bruton's tyrosine kinase within the transcriptional regulator BAP/TFII-IA crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activationThe proline rich region of the Tec homology domain of ITK regulates its activityLck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activityThe role of Tec protein-tyrosine kinase in T cell signalingPKCbeta modulates antigen receptor signaling via regulation of Btk membrane localizationA specific role of phosphatidylinositol 3-kinase gamma. A regulation of autonomic Ca(2)+ oscillations in cardiac cellsCharacterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cellsDistinct aggregation of beta- and gamma-chains of the high-affinity IgE receptor on cross-linkingIdentification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse BtkIndependent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and NckANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain libraryAutoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate.Regulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis.Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker.Localization of Tec29 to ring canals is mediated by Src64 and PtdIns(3,4,5)P3-dependent mechanisms.Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering.Itk phosphorylation sites are required for functional activity in primary T cells.Both proline-rich sequences in the TH region of Bruton's tyrosine kinase stabilize intermolecular interactions with the SH3 domain.
P2860
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P2860
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
description
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 1996
@ast
im Februar 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/02/09)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/02/09)
@nl
наукова стаття, опублікована в лютому 1996
@uk
name
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@ast
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@en
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@nl
type
label
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@ast
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@en
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@nl
prefLabel
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@ast
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@en
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@nl
P2093
P921
P1433
P1476
Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
@en
P2093
A. C. Fluckiger
A. M. Scharenberg
D. J. Rawlings
J. P. Kinet
M. I. Wahl
O. N. Witte
R. M. Kato
P304
P356
10.1126/SCIENCE.271.5250.822
P407
P577
1996-02-09T00:00:00Z