TACI and BAFF-R mediate isotype switching in B cells - Wikidata - awgldk - TriplyDB

TACI and BAFF-R mediate isotype switching in B cells

TACI and BAFF-R mediate isotype switching in B cells

http://www.wikidata.org/entity/Q36402479

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Screening of functional and positional candidate genes in families with common variable immunodeficiency The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88 Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses Atacicept: targeting B cells in multiple sclerosis Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity B-Cell Activating Factor as a Cancer Biomarker and Its Implications in Cancer-Related Cachexia Profile of atacicept and its potential in the treatment of systemic lupus erythematosus Resolve, revise, and relax: the 3 Rs of B cell repertoire adjustment Effect of TACI signaling on humoral immunity and autoimmune diseases Intestinal antigen-presenting cells in mucosal immune homeostasis: crosstalk between dendritic cells, macrophages and B-cells Intestinal IgA production and its role in host-microbe interaction Toll-like receptor 9, transmembrane activator and calcium-modulating cyclophilin ligand interactor, and CD40 synergize in causing B-cell activation.Protective antiviral antibody responses in a mouse model of influenza virus infection require TACI Affinity of antigen encounter and other early B-cell signals determine B-cell fate.Homeostatic control of B lymphocyte subsets.Intestinal bacteria condition dendritic cells to promote IgA production Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: clinical and immunologic outcomes in heterozygotes.Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps.Airway epithelial cells produce B cell-activating factor of TNF family by an IFN-beta-dependent mechanism.CD40-independent help by memory CD4 T cells induces pathogenic alloantibody but does not lead to long-lasting humoral immunity.Common variable immunodeficiency: etiological and treatment issues.The strength of the antibody response to the nematode Ascaris lumbricoides inversely correlates with levels of B-Cell Activating Factor (BAFF).The role of B cells in solid organ transplantation.B cell TLRs and induction of immunoglobulin class-switch DNA recombination.Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.BAFF promotes Th17 cells and aggravates experimental autoimmune encephalomyelitis Immunoglobulin responses at the mucosal interface.High resolution analysis of the chromatin landscape of the IgE switch region in human B cells Role of B cells in common variable immune deficiency.Lactobacillus gasseri SBT2055 induces TGF-β expression in dendritic cells and activates TLR2 signal to produce IgA in the small intestine.Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency.M cell targeting by a Claudin 4 targeting peptide can enhance mucosal IgA responses Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL.CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination.Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes.A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.

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TACI and BAFF-R mediate isotype switching in B cells

http://www.wikidata.org/entity/Q36402479

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2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

TACI and BAFF-R mediate isotype switching in B cells

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TACI and BAFF-R mediate isotype switching in B cells

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TACI and BAFF-R mediate isotype switching in B cells

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TACI and BAFF-R mediate isotype switching in B cells

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prefLabel

TACI and BAFF-R mediate isotype switching in B cells

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TACI and BAFF-R mediate isotype switching in B cells

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Journal of Experimental Medicine

P1476

TACI and BAFF-R mediate isotype switching in B cells

@en

P2093

Emanuela Castigli

http://www.w3.org/2001/XMLSchema#string

Fatma Dedeoglu

http://www.w3.org/2001/XMLSchema#string

Haifa Jabara

http://www.w3.org/2001/XMLSchema#string

Kong-Peng Lam

http://www.w3.org/2001/XMLSchema#string

Raif S Geha

http://www.w3.org/2001/XMLSchema#string

Richard J Bram

http://www.w3.org/2001/XMLSchema#string

Shengli Xu

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Stephen A Wilson

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Sumi Scott

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P2860

Impaired IgA class switching in APRIL-deficient mice

B cell differentiation and isotype switching is related to division cycle number

BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

Glucocorticoids upregulate CD40 ligand expression and induce CD40L-dependent immunoglobulin isotype switching.

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells.

B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses.

Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor.

BAFF AND APRIL: a tutorial on B cell survival.

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35-39

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10.1084/JEM.20032000

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1

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201

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8101136

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15630136

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2212754

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