The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition - Wikidata - awgldk - TriplyDB

The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition

The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition

http://www.wikidata.org/entity/Q36404693

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Hub and switches: endocannabinoid signalling in midbrain dopamine neurons Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition Prenatal stress and peripubertal stimulation of the endocannabinoid system differentially regulate emotional responses and brain metabolism in mice Inhibition of FAAH and activation of PPAR: new approaches to the treatment of cognitive dysfunction and drug addiction Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders Latest advances in the discovery of fatty acid amide hydrolase inhibitors Potential Therapeutic Value of a Novel FAAH Inhibitor for the Treatment of Anxiety Endocannabinoid-mediated synaptic plasticity and addiction-related behavior The endocannabinoid system in anxiety, fear memory and habituation.The neurobiology of individual differences in complex behavioral traits.Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling.In vivo pharmacology of endocannabinoids and their metabolic inhibitors: therapeutic implications in Parkinson's disease and abuse liability Cannabinoid Regulation of Brain Reward Processing with an Emphasis on the Role of CB1 Receptors: A Step Back into the Future Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality The synthetic cannabinoid WIN 55212-2 differentially modulates thigmotaxis but not spatial learning in adolescent and adult animals.Drug addiction.Cannabidiol in humans-the quest for therapeutic targets Voluntary running in young adult mice reduces anxiety-like behavior and increases the accumulation of bioactive lipids in the cerebral cortex.The role of cannabinoids in modulating emotional and non-emotional memory processes in the hippocampus.Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats Effects of endocannabinoid system modulation on cognitive and emotional behavior Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors.Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function The endocannabinoid transport inhibitor AM404 differentially modulates recognition memory in rats depending on environmental aversiveness.Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice.Cardioprotective effects of fatty acid amide hydrolase inhibitor URB694, in a rodent model of trait anxiety.Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26.The interaction of fatty acid amide hydrolase (FAAH) inhibitors with an anandamide carrier protein using (19)F-NMR.FAAH inhibitor OL-135 disrupts contextual, but not auditory, fear conditioning in rats.Pharmacological modulation of the endocannabinoid signalling alters binge-type eating behaviour in female rats.Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors.An endocannabinoid signaling system modulates anxiety-like behavior in male Syrian hamsters.Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates.Role of endocannabinoid signaling in anxiety and depression.An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics.Translational evidence for the involvement of the endocannabinoid system in stress-related psychiatric illnesses Interactions between environmental aversiveness and the anxiolytic effects of enhanced cannabinoid signaling by FAAH inhibition in rats.Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task.

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P2860

The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition

http://www.wikidata.org/entity/Q36404693

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2007 nî lūn-bûn

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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The endogenous cannabinoid ana ...... de hydrolase (FAAH) inhibition

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The endogenous cannabinoid ana ...... de hydrolase (FAAH) inhibition

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The endogenous cannabinoid ana ...... de hydrolase (FAAH) inhibition

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The endogenous cannabinoid ana ...... de hydrolase (FAAH) inhibition

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J.NEUROPHARM.2007.08.011

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Neuropharmacology

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The endogenous cannabinoid ana ...... de hydrolase (FAAH) inhibition

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Daniele Piomelli

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Eva Mikics

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Gianluigi Tanda

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Jozsef Haller

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Julie Medalie

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Maria Scherma

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Sevil Yasar

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Steven R Goldberg

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Subramanian K Vadivel

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Walter Fratta

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P2860

Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

The molecular logic of endocannabinoid signalling

Modulation of anxiety through blockade of anandamide hydrolysis

Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis.

Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines.

Functional role of high-affinity anandamide transport, as revealed by selective inhibition.

Behavioural and biochemical evidence for signs of abstinence in mice chronically treated with delta-9-tetrahydrocannabinol

Correlated species differences in the effects of cannabinoid ligands on anxiety and on GABAergic and glutamatergic synaptic transmission.

Endocannabinoid system and stress and anxiety responses.

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129-140

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10.1016/J.NEUROPHARM.2007.08.011

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1

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54

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Alexandros Makriyannis

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2007-08-19T00:00:00Z

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5939531

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17904589

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