Locus-specific and activity-independent gene repositioning during early tumorigenesis.
about
Nuclear neighborhoods and gene expressionSpatial Genome Organization and Its Emerging Role as a Potential Diagnosis ToolExpanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cellsDifferential spatial repositioning of activated genes in Biomphalaria glabrata snails infected with Schistosoma mansoniHeterochromatin and gene positioning: inside, outside, any side?Genomic interaction profiles in breast cancer reveal altered chromatin architecture.Disease-specific gene repositioning in breast cancer.Statistical analysis of 3D images detects regular spatial distributions of centromeres and chromocenters in animal and plant nuclei.Functional blockade of α5β1 integrin induces scattering and genomic landscape remodeling of hepatic progenitor cells.Gene positioning.Functional organization and dynamics of the cell nucleus3D shortcuts to gene regulationRanked retrieval of segmented nuclei for objective assessment of cancer gene repositioning.Wide-scale alterations in interchromosomal organization in breast cancer cells: defining a network of interacting chromosomes.Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus.DNA binding sites target nuclear NFATc1 to heterochromatin regions in adult skeletal muscle fibersHeterogeneity in the kinetics of nuclear proteins and trajectories of substructures associated with heterochromatin.Non-random organization of the Biomphalaria glabrata genome in interphase Bge cells and the spatial repositioning of activated genes in cells co-cultured with Schistosoma mansoni.Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elementsLong-Range Chromatin InteractionsIdentification of Gene Positioning Factors Using High-Throughput Imaging Mapping.Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cellsRole of nuclear architecture in epigenetic alterations in cancer.Mapping of lamin A- and progerin-interacting genome regionsThe meaning of gene positioningLocus-specific gene repositioning in prostate cancerInfluence of aging on the quantity and quality of human cardiac stem cellsTissue-of-origin-specific gene repositioning in breast and prostate cancer.Cellular microenvironment controls the nuclear architecture of breast epithelia through β1-integrin.Chromatin dynamics and gene positioning.Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence.Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma.Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells.Contributions of extracellular matrix signaling and tissue architecture to nuclear mechanisms and spatial organization of gene expression controlSpatial organization of genes as a component of regulated expression.The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis.Nuclear morphologies: their diversity and functional relevance.Nuclear organization: taking a position on gene expression.Three-dimensional arrangement of genes involved in lipid metabolism in nuclei of porcine adipocytes and fibroblasts in relation to their transcription level.Transcription-dependent radial distribution of TCF7L2 regulated genes in chromosome territories.
P2860
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P2860
Locus-specific and activity-independent gene repositioning during early tumorigenesis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Locus-specific and activity-independent gene repositioning during early tumorigenesis.
@ast
Locus-specific and activity-independent gene repositioning during early tumorigenesis.
@en
type
label
Locus-specific and activity-independent gene repositioning during early tumorigenesis.
@ast
Locus-specific and activity-independent gene repositioning during early tumorigenesis.
@en
prefLabel
Locus-specific and activity-independent gene repositioning during early tumorigenesis.
@ast
Locus-specific and activity-independent gene repositioning during early tumorigenesis.
@en
P2860
P356
P1476
Locus-specific and activity-independent gene repositioning during early tumorigenesis
@en
P2093
Tom Misteli
P2860
P356
10.1083/JCB.200708204
P407
P577
2008-01-01T00:00:00Z