AZD1775 sensitizes T cell acute lymphoblastic leukemia cells to cytarabine by promoting apoptosis over DNA repair
about
Disulfiram chelated with copper promotes apoptosis in human breast cancer cells by impairing the mitochondria functions.Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination RepairPhosphorylation of H2A.XTyr39 positively regulates DNA damage response and is linked to cancer progression.The cell cycle checkpoint inhibitors in the treatment of leukemias.Upregulation of WEE1 is a potential prognostic biomarker for patients with colorectal cancer.Recent Advances of Cell-Cycle Inhibitor Therapies for Pediatric Cancer.Directing the use of DDR kinase inhibitors in cancer treatment.Increased activity of both CDK1 and CDK2 is necessary for the combinatorial activity of WEE1 inhibition and cytarabine.Chemotherapy-induced differential cell cycle arrest in B cell lymphomas affects their sensitivity to Wee1 inhibition.A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia.Targeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia
P2860
Q36063610-0BC98A7C-6930-4AF0-92A9-A9B3E712C0E2Q36309585-BF1BC914-A423-47E4-B1EF-5E4EDA7D6548Q38732997-9B5A90AB-9A8E-45C6-88C0-37AB8A3EB970Q38868502-4C846077-3AB3-4868-BD1B-1F277FB87BBAQ42231927-40C02827-E5E4-42DB-8AC2-94695351EB92Q47447546-F88D5EC1-385D-494B-990E-99EC060CFCCFQ47687840-A25D832C-471C-4677-BAF7-899D387CC303Q48590181-4D07E7DC-8E3A-4EEF-AB7B-14EA6FC06218Q50020989-0972269E-EF71-4289-9693-8AFF379C019AQ52764412-27977E64-F759-49F4-A7A6-3F2133850E58Q56355417-D31B62BE-C0AF-4FBF-986C-F49836B0DB18
P2860
AZD1775 sensitizes T cell acute lymphoblastic leukemia cells to cytarabine by promoting apoptosis over DNA repair
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2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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name
AZD1775 sensitizes T cell acut ...... ting apoptosis over DNA repair
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AZD1775 sensitizes T cell acut ...... ting apoptosis over DNA repair
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type
label
AZD1775 sensitizes T cell acut ...... ting apoptosis over DNA repair
@ast
AZD1775 sensitizes T cell acut ...... ting apoptosis over DNA repair
@en
prefLabel
AZD1775 sensitizes T cell acut ...... ting apoptosis over DNA repair
@ast
AZD1775 sensitizes T cell acut ...... ting apoptosis over DNA repair
@en
P2093
P2860
P356
P1433
P1476
AZD1775 sensitizes T cell acut ...... ting apoptosis over DNA repair
@en
P2093
Annemie A Van Linden
Christopher C Porter
Dmitry Baturin
James B Ford
Tamara M Burleson
Yong-Mi Kim
P2860
P304
28001-28010
P356
10.18632/ONCOTARGET.4830
P407
P577
2015-08-10T00:00:00Z