Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A
about
An high-throughput in vivo screening system to select H3K4-specific histone demethylase inhibitorsHypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP)Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complexUTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.The Arabidopsis Mediator CDK8 module genes CCT (MED12) and GCT (MED13) are global regulators of developmental phase transitions.Functional Crosstalk Between Lysine Methyltransferases on Histone Substrates: The Case of G9A/GLP and Polycomb Repressive Complex 2Novel Function of Lysine Methyltransferase G9a in the Regulation of Sox2 Protein StabilityInhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping.Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy.EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.AAL exacerbates pro-inflammatory response in macrophages by regulating Mincle/Syk/Card9 signaling along with the Nlrp3 inflammasome assembly.C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association.G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition.KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1G9a, a multipotent regulator of gene expression.UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemiaTissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiationThe methyltransferase G9a regulates HoxA9-dependent transcription in AML.Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells.Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.Deciphering the epigenetic code of T lymphocytes.Regulation of CD4 T-cell differentiation and inflammation by repressive histone methylation.Regulation of cell differentiation and function by the euchromatin histone methyltranserfases G9a and GLP.Sound of silence: the properties and functions of repressive Lys methyltransferases.The expanding role of the Ehmt2/G9a complex in neurodevelopment.Inhibitors of Protein Methyltransferases and Demethylases.Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation.Human EHMT2/G9a activates p53 through methylation-independent mechanism.Role of RBP2-Induced ER and IGF1R-ErbB Signaling in Tamoxifen Resistance in Breast Cancer.Methylation at the CpG island shore region upregulates Nr3c1 promoter activity after early-life stress.Multi-dimensional histone methylations for coordinated regulation of gene expression under hypoxia.
P2860
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P2860
Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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2012年學術文章
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2012年學術文章
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name
Maintenance of gene silencing ...... H3K4 demethylase Jarid1a/KDM5A
@ast
Maintenance of gene silencing ...... H3K4 demethylase Jarid1a/KDM5A
@en
type
label
Maintenance of gene silencing ...... H3K4 demethylase Jarid1a/KDM5A
@ast
Maintenance of gene silencing ...... H3K4 demethylase Jarid1a/KDM5A
@en
prefLabel
Maintenance of gene silencing ...... H3K4 demethylase Jarid1a/KDM5A
@ast
Maintenance of gene silencing ...... H3K4 demethylase Jarid1a/KDM5A
@en
P2093
P2860
P356
P1476
Maintenance of gene silencing ...... H3K4 demethylase Jarid1a/KDM5A
@en
P2093
Brinda Somasundaram
Chandra-Prakash Chaturvedi
F Jeffrey Dilworth
Kulwant Singh
Marjorie Brand
Richard L Carpenedo
William L Stanford
P2860
P304
18845-18850
P356
10.1073/PNAS.1213951109
P407
P577
2012-10-29T00:00:00Z