Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.
about
A single residue differentiates between human cardiac and skeletal muscle Na+ channel slow inactivationA molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channelUltra-slow inactivation in mu1 Na+ channels is produced by a structural rearrangement of the outer vestibuleThe dual role of calcium: pore blocker and modulator of gatingDisrupted coupling of gating charge displacement to Na+ current activation for DIIS4 mutations in hypokalemic periodic paralysisSlow inactivation in human cardiac sodium channelsEnhanced slow inactivation by V445M: a sodium channel mutation associated with myotoniaStructural determinants of slow inactivation in human cardiac and skeletal muscle sodium channels.Voltage-dependent sodium channel function is regulated through membrane mechanics.Isoform-specific lidocaine block of sodium channels explained by differences in gatingRapid and slow voltage-dependent conformational changes in segment IVS6 of voltage-gated Na(+) channelsIon channel associated diseases: overview of molecular mechanismsExtracellular proton modulation of the cardiac voltage-gated sodium channel, Nav1.5.Dopamine receptor activation can reduce voltage-gated Na+ current by modulating both entry into and recovery from inactivationSubunit dependence of Na channel slow inactivation and open channel block in cerebellar neuronsGating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor.Slow inactivation does not affect movement of the fast inactivation gate in voltage-gated Na+ channels.Speeding the recovery from ultraslow inactivation of voltage-gated Na+ channels by metal ion binding to the selectivity filter: a foot-on-the-door?Sodium channel inactivation: molecular determinants and modulation.Use-dependent block of the voltage-gated Na(+) channel by tetrodotoxin and saxitoxin: effect of pore mutations that change ionic selectivity.Block of muscle nicotinic receptors by choline suggests that the activation and desensitization gates act as distinct molecular entities.Inactivation of gating currents of L-type calcium channels. Specific role of the alpha 2 delta subunitInfluence of permeant ions on gating in cyclic nucleotide-gated channels.Interaction between the pore and a fast gate of the cardiac sodium channel.Anomalous effect of permeant ion concentration on peak open probability of cardiac Na+ channels.Extracellular zinc ion inhibits ClC-0 chloride channels by facilitating slow gatingA structural rearrangement in the sodium channel pore linked to slow inactivation and use dependence.Slow inactivation does not block the aqueous accessibility to the outer pore of voltage-gated Na channels.Role of domain 4 in sodium channel slow inactivationMolecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation?Proton sensors in the pore domain of the cardiac voltage-gated sodium channel.Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels I: wild-type skeletal muscle Na(V)1.4.Resurgent Na currents in four classes of neurons of the cerebellum.Inwardly permeating Na ions generate the voltage dependence of resurgent Na current in cerebellar Purkinje neurons.The pore, not cytoplasmic domains, underlies inactivation in a prokaryotic sodium channel.Slow inactivation of the Ca(V)3.1 isotype of T-type calcium channels.Uncoupling of gating charge movement and closure of the ion pore during recovery from inactivation in the Kv1.5 channel.Comparison of aconitine-modified human heart (hH1) and rat skeletal (mu1) muscle Na+ channels: an important role for external Na+ ions.Molecular identification of a TTX-sensitive Ca(2+) current.Lidocaine induces a slow inactivated state in rat skeletal muscle sodium channels.
P2860
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P2860
Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.
@ast
Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.
@en
type
label
Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.
@ast
Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.
@en
prefLabel
Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.
@ast
Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.
@en
P2860
P356
P1476
Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.
@en
P2093
P2860
P356
10.1085/JGP.110.1.23
P577
1997-07-01T00:00:00Z