Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells
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Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells.The mitochondrial Ca2+ uniporter MCU is essential for glucose-induced ATP increases in pancreatic β-cellsThe central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetesEpisodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRH.Action potentials and insulin secretion: new insights into the role of Kv channels.Pancreatic β-cell-specific ablation of TASK-1 channels augments glucose-stimulated calcium entry and insulin secretion, improving glucose tolerance.Slow oscillations of KATP conductance in mouse pancreatic islets provide support for electrical bursting driven by metabolic oscillations.Improving the physiological realism of experimental models.Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta- and delta-cells within intact islets of Langerhans.Glucose modulates [Ca2+]i oscillations in pancreatic islets via ionic and glycolytic mechanisms.Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles.Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channelsMetabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillationsLessons from models of pancreatic beta cells for engineering glucose-sensing cellsThe phantom burster model for pancreatic beta-cellsThree roads to islet bursting: emergent oscillations in coupled phantom burstersCalcium and glycolysis mediate multiple bursting modes in pancreatic islets.Filtering of calcium transients by the endoplasmic reticulum in pancreatic beta-cellsLoperamide mobilizes intracellular Ca2+ stores in insulin-secreting HIT-T15 cells.Electrical bursting, calcium oscillations, and synchronization of pancreatic isletsIonic mechanisms and Ca2+ dynamics underlying the glucose response of pancreatic β cells: a simulation study.Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose HomeostasisModeling of glucose-induced cAMP oscillations in pancreatic β cells: cAMP rocks when metabolism rollsGLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.A computational systems analysis of factors regulating α cell glucagon secretion.Calcium-activated K+ channels of mouse beta-cells are controlled by both store and cytoplasmic Ca2+: experimental and theoretical studies.Pharmacological properties and functional role of Kslow current in mouse pancreatic beta-cells: SK channels contribute to Kslow tail current and modulate insulin secretionFrequency-dependent mitochondrial Ca(2+) accumulation regulates ATP synthesis in pancreatic β cells.Ion channels and regulation of insulin secretion in human β-cells: a computational systems analysisMetabolic and electrical oscillations: partners in controlling pulsatile insulin secretion.PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.Enhanced glucose tolerance by SK4 channel inhibition in pancreatic beta-cells.A model of action potentials and fast Ca2+ dynamics in pancreatic beta-cellsContributions of mathematical modeling of beta cells to the understanding of beta-cell oscillations and insulin secretionBK channels affect glucose homeostasis and cell viability of murine pancreatic beta cells.K(ATP) channels and islet hormone secretion: new insights and controversies.Mathematical models of electrical activity of the pancreatic β-cell: a physiological review.Anoctamin 1 (Ano1) is required for glucose-induced membrane potential oscillations and insulin secretion by murine β-cells.Unperturbed islet α-cell function examined in mouse pancreas tissue slices.
P2860
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P2860
Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Activation of Ca(2+)-dependent ...... in mouse pancreatic beta cells
@ast
Activation of Ca(2+)-dependent ...... in mouse pancreatic beta cells
@en
type
label
Activation of Ca(2+)-dependent ...... in mouse pancreatic beta cells
@ast
Activation of Ca(2+)-dependent ...... in mouse pancreatic beta cells
@en
prefLabel
Activation of Ca(2+)-dependent ...... in mouse pancreatic beta cells
@ast
Activation of Ca(2+)-dependent ...... in mouse pancreatic beta cells
@en
P2093
P2860
P50
P356
P1476
Activation of Ca(2+)-dependent ...... in mouse pancreatic beta cells
@en
P2093
E Renström
J Galvanovskis
P2860
P304
P356
10.1085/JGP.114.6.759
P577
1999-12-01T00:00:00Z