MinK subdomains that mediate modulation of and association with KvLQT1.
about
Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunitsIntracellular domains interactions and gated motions of I(KS) potassium channel subunitsKCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channelDynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2Structure of KCNE1 and Implications for How It Modulates the KCNQ1 Potassium Channel † ‡Expression and coassociation of ERG1, KCNQ1, and KCNE1 potassium channel proteins in horse heartKCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channelPreparation, functional characterization, and NMR studies of human KCNE1, a voltage-gated potassium channel accessory subunit associated with deafness and long QT syndromeFunctional delivery of a membrane protein into oocyte membranes using bicellesConformational changes of an ion-channel during gating and emerging electrophysiologic properties: Application of a computational approach to cardiac Kv7.1.Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel.Inherited and acquired vulnerability to ventricular arrhythmias: cardiac Na+ and K+ channels.Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy.Differential modulations of KCNQ1 by auxiliary proteins KCNE1 and KCNE2Mechanisms of disease pathogenesis in long QT syndrome type 5Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1N-terminal arginines modulate plasma-membrane localization of Kv7.1/KCNE1 channel complexes.Structural investigation of the transmembrane domain of KCNE1 in proteoliposomesKCNE1 remodels the voltage sensor of Kv7.1 to modulate channel function.Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.KCNQ1/KCNE1 assembly, co-translation not required.KCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activity.Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channelReconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environmentsRegulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.Molecular mechanisms underlying KVS-1-MPS-1 complex assembly.Secondary structure of a KCNE cytoplasmic domainProbing the structural basis for differential KCNQ1 modulation by KCNE1 and KCNE2Intracellular trafficking of the KV1.3 potassium channel is regulated by the prodomain of a matrix metalloprotease.KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains.Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines.Building KCNQ1/KCNE1 channel models and probing their interactions by molecular-dynamics simulations.The KCNE Tango - How KCNE1 Interacts with Kv7.1.Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking.Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.Photo-Cross-Linking of IKs Demonstrates State-Dependent Interactions between KCNE1 and KCNQ1.Association of KCNE1 genetic polymorphisms with atrial fibrillation in a Chinese Han population.KCNE3 truncation mutants reveal a bipartite modulation of KCNQ1 K+ channels.Structural models for the KCNQ1 voltage-gated potassium channel.
P2860
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P2860
MinK subdomains that mediate modulation of and association with KvLQT1.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
MinK subdomains that mediate modulation of and association with KvLQT1.
@ast
MinK subdomains that mediate modulation of and association with KvLQT1.
@en
type
label
MinK subdomains that mediate modulation of and association with KvLQT1.
@ast
MinK subdomains that mediate modulation of and association with KvLQT1.
@en
prefLabel
MinK subdomains that mediate modulation of and association with KvLQT1.
@ast
MinK subdomains that mediate modulation of and association with KvLQT1.
@en
P2860
P356
P1476
MinK subdomains that mediate modulation of and association with KvLQT1.
@en
P2093
A L George
A R Tapper
P2860
P304
P356
10.1085/JGP.116.3.379
P577
2000-09-01T00:00:00Z