Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway.
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Fast- or slow-inactivated state preference of Na+ channel inhibitors: a simulation and experimental studyLocating the route of entry and binding sites of benzocaine and phenytoin in a bacterial voltage gated sodium channelCardiac Na Channels: Structure to FunctionState-Dependent Modification of Voltage-Gated Sodium Channels by Pyrethroids.Molecular mechanism of allosteric modification of voltage-dependent sodium channels by local anestheticsReporting sodium channel activity using calcium flux: pharmacological promiscuity of cardiac Nav1.5.Mechanisms of atrial-selective block of Na⁺ channels by ranolazine: II. Insights from a mathematical modelMolecular mechanisms of pyrethroid insecticide neurotoxicity: recent advances.Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor.State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channelMutant bacterial sodium channels as models for local anesthetic block of eukaryotic proteinsPersistent human cardiac Na+ currents in stably transfected mammalian cells: Robust expression and distinct open-channel selectivity among Class 1 antiarrhythmics.Block of human cardiac sodium channels by lacosamide: evidence for slow drug binding along the activation pathway.The sodium channel as a target for local anesthetic drugs.Preferential block of inactivation-deficient Na+ currents by capsaicin reveals a non-TRPV1 receptor within the Na+ channel.State-Dependent Inhibition of Sodium Channels by Local Anesthetics: A 40-Year Evolution.Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics.The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity.Mechanisms of Drug Binding to Voltage-Gated Sodium Channels.
P2860
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P2860
Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
Block of inactivation-deficien ...... along the activation pathway.
@ast
Block of inactivation-deficien ...... along the activation pathway.
@en
type
label
Block of inactivation-deficien ...... along the activation pathway.
@ast
Block of inactivation-deficien ...... along the activation pathway.
@en
prefLabel
Block of inactivation-deficien ...... along the activation pathway.
@ast
Block of inactivation-deficien ...... along the activation pathway.
@en
P2093
P2860
P356
P1476
Block of inactivation-deficien ...... along the activation pathway.
@en
P2093
Edward Moczydlowski
Ging Kuo Wang
Jane Mitchell
Sho-Ya Wang
P2860
P304
P356
10.1085/JGP.200409128
P577
2004-11-15T00:00:00Z