Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis.
about
The protein kinase IKKepsilon regulates energy balance in obese miceHerbal medicines for the treatment of nonalcoholic steatohepatitis: current scenario and future prospectsSimple sugar intake and hepatocellular carcinoma: epidemiological and mechanistic insightGenetically modified mouse models for the study of nonalcoholic fatty liver diseaseMyeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistanceImplication of inflammatory signaling pathways in obesity-induced insulin resistanceImpaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesityDietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expressionMechanisms for insulin resistance: common threads and missing linksMacrophage function in obesity-induced inflammation and insulin resistance.Genome-wide mRNA expression analysis of hepatic adaptation to high-fat diets reveals switch from an inflammatory to steatotic transcriptional program.Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes.TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesisCell penetrating peptide inhibitors of nuclear factor-kappa B.An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in miceAlteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in miceThe metabolically benign and malignant fatty liver.Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticalsNF-κB in the liver--linking injury, fibrosis and hepatocellular carcinoma.Cancer microenvironment and cancer vaccine.Correlation between blood activin levels and clinical parameters of type 2 diabetes.Prohibitin-induced, obesity-associated insulin resistance and accompanying low-grade inflammation causes NASH and HCCRutaecarpine ameliorates hyperlipidemia and hyperglycemia in fat-fed, streptozotocin-treated rats via regulating the IRS-1/PI3K/Akt and AMPK/ACC2 signaling pathwaysMurine Models of Nonalcoholic Fatty Liver Disease and Steatohepatitis.Obesity, cancer, and acetyl-CoA metabolism.PPARs Mediate Lipid Signaling in Inflammation and Cancer.Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis.The Role of NF-kappaB in PPARalpha-Mediated Hepatocarcinogenesis.Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6KDiet-induced obesity increases NF-kappaB signaling in reporter mice.Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1.Obesity, inflammation, and liver cancer.MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity.Small-molecule inhibitors of PKR improve glucose homeostasis in obese diabetic mice.The Role of Immunogenicity in Cardiovascular Disease.Role of nuclear factor kappaB in liver health and disease.NF-κB, inflammation, and metabolic disease.Dissociating fatty liver and diabetesGlucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes.TNF-dependent signaling pathways in liver cancer: promising targets for therapeutic strategies?.
P2860
Q24658201-123DA21C-16A4-4893-A19E-C8F35E99FC26Q26828615-5E41CB9B-14EB-478A-8016-F5D96AFBAE14Q26864513-B6AD19F2-C0A2-4C7E-9A09-D921B4E93F1EQ26865248-3D76F810-B3E3-4D29-B740-50BB228A8AF3Q27347641-49A266E1-DB8F-41BC-8320-69C7EB80A171Q27500365-9737BF53-1EFC-462F-AE51-30AA256A61C3Q28281865-5F67FB70-2CEF-4450-829E-1B5BA95C0CD9Q29615766-CBE72773-A05F-4A87-BB8A-33BCA10B7BE3Q29620447-3651F090-7DFD-47FC-9ED3-B9E839FEF1EEQ30235587-9B508223-CE82-47A1-837A-F617670E6276Q33493427-4072322B-5CBA-41D2-B46E-CCC8A37DB2C4Q33536636-C06A1971-39FA-4263-96D4-6AD6192AC968Q33944283-EDE58819-3814-4BF8-BCBA-8A1E16E16988Q34289086-5035793E-8D4E-475F-A76F-36338D2F3473Q34327061-B6844D63-9CBC-40B7-9C8B-09124E73D488Q34562825-84A59115-C98A-4652-96B6-95FD0708EED9Q35123495-1F3DD3CD-84A9-4C5C-B295-5E1C93459A08Q35129349-23A13E7A-FD37-4C70-AE72-DF183B515097Q35808323-0882E98B-C1E2-4C87-8C2C-FA1F5BBA0596Q36284923-9220F131-70C6-4342-90F0-262DB758B576Q36497833-E7146E04-FA77-46A9-B488-8CDE14FAE849Q36719439-5C2294FD-6B4B-41D0-8CBB-8AC52C98AC60Q36765138-D791BC29-C722-4510-9EAD-0F2F934E9608Q36961972-782DD867-6C9E-4CD4-ADBA-25FED2FE1B2DQ37020606-5E6245C3-5E06-41F8-BDAA-AEB6DCFF3197Q37021709-C180A6D8-9DF1-4880-8FDB-6CBE0858E5A6Q37039574-A6707DE9-2940-4E91-95EA-FAF07F38C510Q37078825-5DC0A7DD-C420-4916-82C5-EBA7ACFE8E43Q37258467-5AEA712B-DC96-4421-BE7E-86E6EF9E6A5FQ37350810-759A571F-76D0-4B95-9AB0-67B60F5BC3ECQ37406466-38458B46-361D-401D-89F4-38F0E469A02EQ37469981-BBB499AA-DA4C-4AE0-ADDB-6AD30A04B570Q37502701-6FBEE964-A216-4B0D-828C-43B6CB3C74ECQ37510143-1923C430-850A-4D31-B503-B12E8ABD835DQ37560012-FF1AD3AF-5350-4F07-B35F-0062EE136B99Q37720780-96CE3A96-0C14-4A22-B59C-F10484CB93A8Q37825008-12F26BBD-E6AE-4C33-A3D6-06BF854DD99DQ38050214-AC5B7178-4A88-454D-98AA-2FC89F77D701Q38324231-BDB97363-47F8-4B5E-B805-4A4F189FB9FCQ39529070-47010D7F-9476-4882-872B-8526F0A8C9A7
P2860
Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Hepatic NF-kappa B essential m ...... -fat feeding in tumorigenesis.
@ast
Hepatic NF-kappa B essential m ...... -fat feeding in tumorigenesis.
@en
type
label
Hepatic NF-kappa B essential m ...... -fat feeding in tumorigenesis.
@ast
Hepatic NF-kappa B essential m ...... -fat feeding in tumorigenesis.
@en
prefLabel
Hepatic NF-kappa B essential m ...... -fat feeding in tumorigenesis.
@ast
Hepatic NF-kappa B essential m ...... -fat feeding in tumorigenesis.
@en
P2093
P2860
P50
P921
P356
P1476
Hepatic NF-kappa B essential m ...... -fat feeding in tumorigenesis.
@en
P2093
F Thomas Wunderlich
Julia Baumgartl
Marc Schmidt-Supprian
Peter Schirmacher
Stephan Singer
Tom Luedde
P2860
P304
P356
10.1073/PNAS.0707849104
P407
P577
2008-01-23T00:00:00Z