Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosis
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Pathogenic Acinetobacter: from the Cell Surface to Infinity and BeyondCode blue: Acinetobacter baumannii, a nosocomial pathogen with a role in the oral cavityAcinetobacter baumannii: evolution of a global pathogenLipopolysaccharide transport to the cell surface: periplasmic transport and assembly into the outer membrane.Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment OptionsVaccines for Acinetobacter baumannii: thinking "out of the box".Selectable Markers for Use in Genetic Manipulation of Extensively Drug-Resistant (XDR) Acinetobacter baumannii HUMC1.The future of antibioticsSevere Acinetobacter baumannii sepsis is associated with elevation of pentraxin 3.LpxC inhibitors as new antibacterial agents and tools for studying regulation of lipid A biosynthesis in Gram-negative pathogens.Local inflammation exacerbates the severity of Staphylococcus aureus skin infection.Antibiotic modulation of capsular exopolysaccharide and virulence in Acinetobacter baumanniiUnexpected challenges in treating multidrug-resistant Gram-negative bacteria: resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa.Novel approaches are needed to develop tomorrow's antibacterial therapiesVariation in the OC locus of Acinetobacter baumannii genomes predicts extensive structural diversity in the lipooligosaccharide.Host fate is rapidly determined by innate effector-microbial interactions during Acinetobacter baumannii bacteremiaCryopreservation of virulent Acinetobacter baumannii to reduce variability of in vivo studies.Toll-Like Receptor 9 Contributes to Defense against Acinetobacter baumannii Infection.Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606.The TIR Homologue Lies near Resistance Genes in Staphylococcus aureus, Coupling Modulation of Virulence and Antimicrobial Susceptibility.Lipopolysaccharide-deficient Acinetobacter baumannii shows altered signaling through host Toll-like receptors and increased susceptibility to the host antimicrobial peptide LL-37.The future of antibiotics and resistance.Biofilm-Related Genes: Analyses in Multi-Antibiotic Resistant Acinetobacter Baumannii Isolates From Mainland ChinaEfficacy of Lysophosphatidylcholine in Combination with Antimicrobial Agents against Acinetobacter baumannii in Experimental Murine Peritoneal Sepsis and Pneumonia Models.Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumanniiEffects of silver nanoparticles in combination with antibiotics on the resistant bacteria Acinetobacter baumannii.Biological cost of different mechanisms of colistin resistance and their impact on virulence in Acinetobacter baumannii.On the essentiality of lipopolysaccharide to Gram-negative bacteria.Prevalence and Genetic Characterization of Carbapenem- and Polymyxin-Resistant Acinetobacter baumannii Isolated from a Tertiary Hospital in Terengganu, MalaysiaThe Nod1, Nod2, and Rip2 axis contributes to host immune defense against intracellular Acinetobacter baumannii infectionTranslational deficiencies in antibacterial discovery and new screening paradigms.LpxC inhibitors: a patent review (2010-2016).New molecules and adjuvants in the treatment of infections by Acinetobacter baumannii.Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.Activity of host antimicrobials against multidrug-resistant Acinetobacter baumannii acquiring colistin resistance through loss of lipopolysaccharide.Structure, inhibition, and regulation of essential lipid A enzymes.Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges.Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance.Diabetes Exacerbates Infection via Hyperinflammation by Signaling through TLR4 and RAGE.Essential genome of Campylobacter jejuni.
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P2860
Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosis
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Inhibition of LpxC protects mi ...... ion and enhancing phagocytosis
@ast
Inhibition of LpxC protects mi ...... ion and enhancing phagocytosis
@en
type
label
Inhibition of LpxC protects mi ...... ion and enhancing phagocytosis
@ast
Inhibition of LpxC protects mi ...... ion and enhancing phagocytosis
@en
prefLabel
Inhibition of LpxC protects mi ...... ion and enhancing phagocytosis
@ast
Inhibition of LpxC protects mi ...... ion and enhancing phagocytosis
@en
P2093
P2860
P921
P356
P1433
P1476
Inhibition of LpxC protects mi ...... ion and enhancing phagocytosis
@en
P2093
Andrew Tomaras
Beverlie Baquir
Brad Spellberg
Brandon Tan
Elsa G Barbacci
Justin I Montgomery
Kristine Hujer
Lucia Fernandez
Mark D Adams
P2860
P356
10.1128/MBIO.00312-12
P577
2012-10-02T00:00:00Z